通过荧光原位杂交（FISH）对转基因小鼠中的人血管紧张素原基因和人肾素基因进行染色体定位。
Chromosomal mapping of human angiotensinogen gene and human renin gene by fluorescence in situ hybridization (FISH) in transgenic mice.
作者信息
Watanabe Y, Ebukuro M, Yagami K, Sugiyama F, Ishida J, Murakami K, Nomura T, Katoh H
机构信息
Department of Genetics, Central Institute for Experimental Animals, Kanagawa, Japan.
出版信息
Exp Anim. 1996 Jul;45(3):265-9. doi: 10.1538/expanim.45.265.
PMID:8840145
Abstract
We attempted to apply FISH to chromosomal mapping of the human angiotensinogen (hAG) and human renin (hRN) transgenes which are carried by the parental strains of the Tsukuba hypertensive mouse. We report here that the hAG gene is mapped in the C2 region of Chr 19 and the hRN gene in the A1 region of Chr 6.
摘要
我们试图将荧光原位杂交（FISH）应用于筑波高血压小鼠亲本品系所携带的人血管紧张素原（hAG）和人肾素（hRN）转基因的染色体定位。我们在此报告，hAG基因定位于19号染色体的C2区域，hRN基因定位于6号染色体的A1区域。
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