Bubien R S, Knotts-Dolson S M, Plumb V J, Kay G N
Department of Medicine, University of Alabama at Birmingham 35294, USA.
Circulation. 1996 Oct 1;94(7):1585-91. doi: 10.1161/01.cir.94.7.1585.
Although radiofrequency catheter ablation can be used to effectively treat a variety of arrhythmias, the effects of this procedure on health-related quality of life have not been systematically studied.
The SF-36 (a measure of general health status), the Symptom Checklist-Frequency and Severity Scale (an instrument specific for cardiac arrhythmias), and an Activities of Daily Living questionnaire were used to assess quality of life in 161 patients before radiofrequency catheter ablation. These same instruments were used to measure quality of life 1 and 6 months after ablation with complete data in 159 of the original 161 patients. Before ablation, SF-36 scores of the study population were low compared with the US normative data base reflecting significant impairment in physical functioning and well-being. The lowest scores were reported by patients with atrial fibrillation and atrial flutter. Catheter ablation was associated with significant improvement in quality of life that was sustained over the 6 months after ablation. Improvements were measured in both the generic SF-36 health status questionnaire and the disease-specific Symptom Checklist-Frequency and Severity Scale. Catheter ablation was followed by improved performance of activities of daily living and a marked decrease in the number of visits to physicians and emergency rooms in the 6 months after ablation compared with the 6 months before ablation.
Radiofrequency catheter ablation improves the health-related quality of life for patients with a variety of cardiac arrhythmias.
尽管射频导管消融可有效治疗多种心律失常,但该手术对健康相关生活质量的影响尚未得到系统研究。
采用SF-36(一种衡量总体健康状况的指标)、症状清单-频率与严重程度量表(一种专门用于心律失常的工具)以及日常生活活动问卷,对161例患者在射频导管消融术前的生活质量进行评估。在最初的161例患者中,有159例患者在消融术后1个月和6个月时使用相同工具测量生活质量,并获得完整数据。与美国标准数据库相比,消融术前研究人群的SF-36评分较低,反映出身体功能和幸福感存在显著损害。房颤和房扑患者的评分最低。导管消融与生活质量的显著改善相关,且这种改善在消融术后6个月内持续存在。在通用的SF-36健康状况问卷和特定疾病的症状清单-频率与严重程度量表中均有改善。与消融术前6个月相比,导管消融术后6个月患者的日常生活活动能力得到改善,就诊和急诊次数显著减少。
射频导管消融可改善多种心律失常患者的健康相关生活质量。