在高温条件下，苯菌灵DF制剂中自发形成N，N'-二丁基脲（DBU）

Spontaneous N,N'-dibutylurea (DBU) formation in Benlate DF formulation under elevated temperatures.

作者信息

Tang C S, Song L W

机构信息

Department of Environmental Biochemistry, College of Tropical Agriculture and Human Resources, University of Hawaii, Honolulu 96822, USA.

出版信息

Arch Environ Contam Toxicol. 1996 Mar;30(3):403-6. doi: 10.1007/BF00212300.

DOI:10.1007/BF00212300

PMID:8854971

Abstract

Thermal degradation of benomyl in the fungicide Benlate DF at temperatures higher than 55 degrees C leads to the formation of N,N' -dibutylurea (DBU). External moisture is not required, since starch, an "inert" ingredient in the formulation, serves as a source of water. Enhanced phytotoxicity of the heat-treated, DBU-rich Benlate DF was demonstrated by lettuce seedling bioassay. Temperatures higher than 70 degrees C were recorded in a metal shipping container in June 1995 in Hawaii. Accumulation of DBU was observed in Benlate DF sealed in ampules and stored in this container. It is concluded that DBU formation is an intrinsic characteristic of Benlate DF at the temperatures tested. High temperature and high humidity in tropical regions provide ideal conditions for DBU formation in Benlate DF.

摘要

在高于55摄氏度的温度下，杀菌剂苯菌灵干粉剂中的苯菌灵发生热降解，会生成N,N'-二丁基脲（DBU）。由于配方中的“惰性”成分淀粉可作为水源，因此不需要外部水分。通过生菜幼苗生物测定法证明了经热处理且富含DBU的苯菌灵干粉剂具有更强的植物毒性。1995年6月，夏威夷一个金属运输集装箱内记录到温度高于70摄氏度。在密封于安瓿瓶并储存在该集装箱中的苯菌灵干粉剂中观察到了DBU的积累。得出的结论是，在所测试的温度下，DBU的形成是苯菌灵干粉剂的一个固有特性。热带地区的高温高湿为苯菌灵干粉剂中DBU的形成提供了理想条件。