Brucker-Davis F, Reynolds J C, Skarulis M C, Fraker D L, Alexander H R, Weintraub B D, Robbins J
Molecular and Cellular Endocrinology Branch, National Institute of Diabetes and Digestive and Kidney Disease, National Institutes of Health (NIH), Bethesda, MD 20892-1770, USA.
J Nucl Med. 1996 Oct;37(10):1690-3.
False-positive whole-body 131I scans are not frequent but have serious consequences in the management of patients with thyroid cancer. They can be classified in four main groups: elimination of iodine in body fluids, infection or inflammation, cysts or transudates and nonthyroid tumors. We report on two patients with false-positive post-therapy 131I scans. The first patient had uptake projected in the right pelvic area which was later proven to be a large gluteal sebaceous cyst. The second patient had uptake in the gallbladder area that did not disappear after 131I treatment; she underwent exploratory laparotomy which revealed extensive chronic cholecystitis. These cases illustrate two new causes of false-positive 131I whole-body scans (sebaceous cyst and cholecystitis), which highlights two mechanisms (elimination in body fluid and inflammation).
假阳性的全身碘-131扫描并不常见，但在甲状腺癌患者的治疗管理中会产生严重后果。它们可主要分为四类：体液中碘的清除、感染或炎症、囊肿或漏出液以及非甲状腺肿瘤。我们报告了两例治疗后碘-131扫描假阳性的患者。第一例患者的摄取影像显示在右盆腔区域，后来证实是一个巨大的臀皮脂腺囊肿。第二例患者胆囊区域有摄取，碘-131治疗后仍未消失；她接受了剖腹探查术，结果显示为广泛的慢性胆囊炎。这些病例说明了碘-131全身扫描假阳性的两个新原因（皮脂腺囊肿和胆囊炎），突出了两种机制（体液清除和炎症）。
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