Powell B C, Maull K I, Sachatello C R
South Med J. 1977 Aug;70(8):935-7. doi: 10.1097/00007611-197708000-00010.
When squamous metaplasia of the lactiferous ducts occurs, the normal cuboidal epithelium lining the lactiferous ducts is replaced by squamous epithelium, leading to intraluminal accumulation of epithelial debris. Recurrent subareolar abscess is a common co-feature of the disease. The chronicity of suppuration is related to a general unfamiliarity with this entity and its underlying pathogenesis and failure to recognize the inadequacy of simple incision and drainage. Recent experience with six patients with recurrent subareolar abscess suggests that cure requires excision of the disease duct(s) and abscess cavity in continuity with the nipple inversion, which also is seen with this problem. The clinical triad of recurrent subareolar abscess, intermittent periareolar drainage, and (possibly) nipple inversion should alert the practitioner to this entity. Appropriate initial operative management will minimize recurrence.
当输乳管发生鳞状化生时，输乳管内衬的正常立方上皮被鳞状上皮取代，导致管腔内上皮碎屑积聚。复发性乳晕下脓肿是该疾病的常见共同特征。化脓的慢性化与对该疾病及其潜在发病机制普遍不熟悉以及未能认识到单纯切开引流的不足有关。最近对6例复发性乳晕下脓肿患者的经验表明，治愈需要切除病变导管和脓肿腔，并与乳头内陷一并切除，乳头内陷在该问题中也可见。复发性乳晕下脓肿、间歇性乳晕周围引流和（可能）乳头内陷的临床三联征应提醒从业者注意该疾病。适当的初始手术管理将使复发风险降至最低。
