Schumpelick V, Braun J
Chirurgische Klinik, RWTH Aachen.
Chirurg. 1996 Feb;67(2):110-20.
The tendency toward sphincter-preserving resection for distal rectal cancers has led in recent years to a revival of the technique of coloanal anastomosis (CAA). Our experience with intersphincteric resection in combination with CAA was reviewed with the aim of assessing morbidity, functional outcome, and cancer treatment results. A total of 119 patients treated for primary rectal cancer by CAA between 1978 and 1994 were studied retrospectively. Seventy-six percent of the tumors were located in the lower third of the rectum. There were 4 (3.3%) deaths. The most common postoperative complications were urinary retention (13.5%) and sexual dysfunction (17%). There were 10 patients (8.4%) with clinical anastomic leaks and 3 patients (2.5%) with symptomatic stricture. General complications occured in 33 patients (28%). The mean stool frequency was 2.2 per day. Twenty-three percent of patients reported 4 or more stools per day. Fecal continence was complete in 69%, incontinence to gas in 10%, minor leak in 17% and major soiling in 4%. Urgency occurred in 14% and incomplete evacuation was present in 27%. The cumulative local recurrence rate was 8.7%, 5-year survival was 71% (Dukes A 100%, Dukes B 89%, Dukes C 48%). Interspincteric resection combined with CAA provides excellent treatment for low rectal cancers with long-term preservation of sphincter function and satisfactory local and distant tumor control.
近年来,由于对低位直肠癌行保留括约肌切除术的趋势,使得结肠肛管吻合术(CAA)这项技术得以复兴。我们回顾了括约肌间切除术联合CAA的经验,目的是评估其发病率、功能结局和癌症治疗效果。对1978年至1994年间119例接受CAA治疗原发性直肠癌的患者进行了回顾性研究。76%的肿瘤位于直肠下三分之一处。有4例(3.3%)死亡。最常见的术后并发症是尿潴留(13.5%)和性功能障碍(17%)。有10例患者(8.4%)出现临床吻合口漏,3例患者(2.5%)出现有症状的狭窄。33例患者(28%)发生一般并发症。平均每日排便次数为2.2次。23%的患者报告每日排便4次或更多。69%的患者大便完全自控,10%的患者有气体失禁,17%的患者有少量渗漏,4%的患者有严重污染。14%的患者出现便急,27%的患者有排便不净。局部复发累积率为8.7%,5年生存率为71%(Dukes A期100%,Dukes B期89%,Dukes C期48%)。括约肌间切除术联合CAA为低位直肠癌提供了良好的治疗方法,可长期保留括约肌功能,并能实现满意的局部和远处肿瘤控制。