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智力障碍成年人中的运动障碍性运动障碍:现象学及与刻板动作的共现情况

Dyskinetic movement disorder among adults with mental retardation: phenomenology and co-occurrence with stereotypy.

作者信息

Bodfish J W, Newell K M, Sprague R L, Harper V N, Lewis M H

机构信息

Western Carolina Center, Morganton, NC, USA.

出版信息

Am J Ment Retard. 1996 Sep;101(2):118-29.

PMID:8883667
Abstract

We screened for the occurrence of dyskinetic and stereotypic movement disorders using item-independent screening protocols to determine whether these forms of movement disorder can be distinguished among adults with mental retardation. Stereotypies and dyskinesias were reliably distinguished in terms of topography. Tardive dyskinesia occurred in 18.2% of a cohort of individuals receiving chronic neuroleptic treatment. Stereotypic movement disorder was associated with increased dyskinesia scores and increased prevalence of tardive dyskinesia. Increased dyskinesia scores were also found for subjects exhibiting stereotypy who had been free of neuroleptic treatment for 3 years. Results indicate that dyskinesia and stereotypy are discriminable movement disorders and provide preliminary support for the hypothesis that they may be related by common mechanisms.

摘要

我们使用与项目无关的筛查方案来筛查运动障碍和刻板运动障碍的发生情况,以确定这些运动障碍形式在智力障碍成年人中是否可以区分。刻板动作和运动障碍在形态学上能够可靠地区分。在接受慢性抗精神病药物治疗的一组个体中,迟发性运动障碍的发生率为18.2%。刻板运动障碍与运动障碍评分增加和迟发性运动障碍患病率增加有关。在3年未接受抗精神病药物治疗且表现出刻板动作的受试者中,也发现了运动障碍评分增加的情况。结果表明,运动障碍和刻板动作是可区分的运动障碍,并为它们可能通过共同机制相关的假说提供了初步支持。

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