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寄生虫侵袭中的免疫反应(作者译)

[Immunologic reaction in parasitic invasion (author's transl)].

作者信息

Zwisler O

出版信息

Z Parasitenkd. 1977 Jun 3;52(1):1-10. doi: 10.1007/BF00380552.

DOI:10.1007/BF00380552
PMID:888505
Abstract

Among the manifold immunologic events which take place during parasitic invasions, production of autoantibodies and immune complexes can play a serious role during infections with African and American trypanosomes. The importance of complement deserves new attention. The increasing level of IgE induced by helminthic infections on a humoral basis seems to be caused by separate worm allergens; its involvement in self-cure phenomena together with processes on cellular levels is discussed. Destructive processes on various development stages of schistosoma and immunological events during cutaneous leishmaniasis are also cell mediated. Variations in the antigenic behaviour of parasites and their immunological mimicry by uptake of substances from the host and their immunosuppressive action are discussed. As reasons for absence of immunity against animal parasites this action can disturb either humoral or cellular immunological procedures or both.

摘要

在寄生虫入侵过程中发生的众多免疫事件中,自身抗体和免疫复合物的产生在非洲和美洲锥虫感染期间可能起重要作用。补体的重要性值得重新关注。蠕虫感染在体液基础上诱导的IgE水平升高似乎是由不同的蠕虫过敏原引起的;本文讨论了其在自愈现象中的作用以及与细胞水平过程的关系。血吸虫不同发育阶段的破坏过程以及皮肤利什曼病期间的免疫事件也是细胞介导的。本文还讨论了寄生虫抗原行为的变化、它们通过摄取宿主物质进行的免疫模拟及其免疫抑制作用。作为对动物寄生虫缺乏免疫力的原因,这种作用可能会干扰体液或细胞免疫程序,或两者皆有。

相似文献

1
[Immunologic reaction in parasitic invasion (author's transl)].寄生虫侵袭中的免疫反应(作者译)
Z Parasitenkd. 1977 Jun 3;52(1):1-10. doi: 10.1007/BF00380552.
2
Effective and ineffective immune responses to parasites: evidence from experimental models.对寄生虫的有效和无效免疫反应:来自实验模型的证据。
Curr Top Microbiol Immunol. 1978;80:37-64. doi: 10.1007/978-3-642-66956-9_2.
3
Antigenic glycans in parasitic infections: implications for vaccines and diagnostics.寄生虫感染中的抗原聚糖:对疫苗和诊断的影响。
Arch Biochem Biophys. 2004 Jun 15;426(2):182-200. doi: 10.1016/j.abb.2004.04.004.
4
Humoral immune response in parasitic infections.寄生虫感染中的体液免疫反应。
Southeast Asian J Trop Med Public Health. 1978 Jun;9(2):142-52.
5
IgE and mast cells in host defense against parasites and venoms.免疫球蛋白E和肥大细胞在宿主抵御寄生虫和毒液中的作用。
Semin Immunopathol. 2016 Sep;38(5):581-603. doi: 10.1007/s00281-016-0565-1. Epub 2016 May 25.
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Evolutionary immune response to conserved domains in parasites and aeroallergens.对寄生虫和空气过敏原中保守结构域的进化免疫反应。
Allergy Asthma Proc. 2013 Jan-Feb;34(1):93-102. doi: 10.2500/aap.2013.34.3616.
7
Evasion of the immune response by parasites.寄生虫对免疫反应的逃避
Br Med Bull. 1976 May;32(2):177-81. doi: 10.1093/oxfordjournals.bmb.a071352.
8
Protection tests against parasitic diseases.针对寄生虫病的防护测试。
Comp Immunol Microbiol Infect Dis. 1986;9(2-3):217-23. doi: 10.1016/0147-9571(86)90014-7.
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[The evolution of the Th2 immune responses and its relationships with parasitic diseases and allergy].[Th2免疫反应的演变及其与寄生虫病和过敏的关系]
Biomedica. 2012 Jan-Mar;32(1):145-57. doi: 10.1590/S0120-41572012000100017.
10
Immunology of parasitic infections.寄生虫感染的免疫学
Med Clin North Am. 1985 Jul;69(4):751-8. doi: 10.1016/s0025-7125(16)31017-3.

本文引用的文献

1
Reaginic antibodies and immunity to Nippostrongylus brasiliensis in the rat. II. Some properties of the antibodies and antigens.大鼠体内针对巴西日圆线虫的反应素抗体与免疫性。II. 抗体和抗原的一些特性。
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Mast cells and macromolecular leak in intestinal immunological reactions. The influence of sex of rats infected with Nippostrongylus brasiliensis.肠道免疫反应中的肥大细胞与大分子渗漏。感染巴西日圆线虫的大鼠性别影响
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Protective immunity to Nippostrongylus brasiliensis in the rat. 3. Modulation of worm acetylcholinesterase by antibodies.大鼠对巴西日圆线虫的保护性免疫。3. 抗体对蠕虫乙酰胆碱酯酶的调节作用。
Immunology. 1972 Jan;22(1):119-29.
7
The immunology of nematode infections. Trichinosis in guinea-pigs as a model.线虫感染的免疫学。以豚鼠旋毛虫病作为模型
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8
Schistosoma mansoni: immunity in Macaca mulatta.曼氏血吸虫:恒河猴的免疫
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9
Murine malaria. IV. Disturbed immunological responsiveness during Plasmodium berghei infection.鼠疟。IV. 伯氏疟原虫感染期间免疫反应紊乱。
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Some principles of the immunology of trypanosomiasis.锥虫病免疫学的一些原理。
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