Hounshell C V, Chetkowski R J
Alta Bates In Vitro Fertilization Program, Berkeley, California, USA.
Fertil Steril. 1996 Nov;66(5):837-8.
To determine the availability of donated cryopreserved embryos.
Retrospective review.
Community hospital-based IVF-ET program.
Eighty-three consecutive infertile couples who had 98 sets of embryos cryopreserved after IVF-ET and GIFT between January 1, 1989 and December 31, 1991.
INTERVENTION(S): Cryopreservation of fertilized oocytes or cleaving embryos after IVF-ET and GIFT.
MAIN OUTCOME MEASURE(S): Disposition of frozen embryos as of December 31, 1995.
RESULT(S): Of 98 sets of frozen embryos, 71 (72.4%) were thawed for transfer into the infertile woman. At an average of 6 years since the treatment cycle, six sets of embryos (6.1%) remain in storage. Of 21 sets of embryos not thawed for autologous transfer, the majority (17.4%) were discarded, leaving only four clutches (4.1%) available for donation.
CONCLUSION(S): Couples who did not use their frozen embryos after IVF-ET and GIFT were four times more likely to destroy them than to donate them.
确定捐赠冷冻胚胎的可用性。
回顾性研究。
社区医院的体外受精-胚胎移植(IVF-ET)项目。
1989年1月1日至1991年12月31日期间,83对连续的不孕夫妇在IVF-ET和配子输卵管内移植(GIFT)后冷冻保存了98组胚胎。
IVF-ET和GIFT后对受精卵或分裂期胚胎进行冷冻保存。
截至1995年12月31日冷冻胚胎的处置情况。
在98组冷冻胚胎中,71组(72.4%)被解冻用于移植到不孕女性体内。自治疗周期平均6年后,有6组胚胎(6.1%)仍在储存中。在21组未解冻用于自体移植的胚胎中,大多数(17.4%)被丢弃,仅有4组(4.1%)可用于捐赠。
IVF-ET和GIFT后未使用冷冻胚胎的夫妇销毁胚胎的可能性是捐赠胚胎的四倍。