Wunder C C, Welch R C
Aviat Space Environ Med. 1977 Aug;48(8):734-6.
Material strength as approximated from bending studies of fresh femurs grew during 1 to 8 weeks of hypergravity at rates which were not measurably affected, even though the animal's body growth was measurably slower. As a result, femurs could support greater ultimate loads, moments, and stresses when compared to control bones of comparable rotational moments of their cross-sectional areas. Chronic centrifugation simulated 3.1 G for 45 male. Swiss Webster mice compared to 37 control animals. Effects were most noticeable after the first week of exposure and for younger animals. Effect were only about 50% that noted in comparable treatment of rats. This suggests that four times more mice than rats may be necessary for space-experiments designed to test the effects of weightlessness.
通过对新鲜股骨进行弯曲研究估算出的材料强度，在1至8周的超重力环境下有所增长，其增长速率未受到显著影响，即便动物的身体生长明显减缓。因此，与具有相同横截面积转动惯量的对照骨骼相比，股骨能够承受更大的极限载荷、力矩和应力。对45只雄性瑞士韦伯斯特小鼠进行慢性离心处理，模拟3.1G的重力环境，与37只对照动物作比较。暴露第一周后以及对较年轻的动物而言，影响最为明显。其影响程度仅约为对大鼠进行类似处理时所观察到的50%。这表明，对于旨在测试失重影响的太空实验来说，所需的小鼠数量可能是大鼠的四倍。
