Wand M
Hartford Hospital, Connecticut, USA.
J Glaucoma. 1996 Oct;5(5):301-7.
To compare surgical results between 3.2- and 6.0-mm incisions in combined phacoemulsification, intraocular lens implant, and trabeculectomy with intraoperative mitomycin-C.
Fifty-seven consecutive eyes of 45 patients in a referral practice underwent combined phacoemulsification, intraocular lens implant, and trabeculectomy with intraoperative mitomycin-C. The first 24 eyes had a 6.0-mm incision and the next 33 eyes had a 3.2-mm incision; the procedures were otherwise identical. The postoperative intraocular pressures, number of antiglaucoma medications, presence of filtration blebs, visual acuity, and complications at 1 day, 1 week, 1 month, and 1 year were subjected to multivariate analysis.
There were no statistical differences in the intraocular pressure control, number of antiglaucoma medications, or presence of filtration bleb between the two groups at any of the postoperative visits. Visual acuity was significantly better (p = 0.02) for the 3.2-mm incision group throughout the evaluation period.
Both large- and small-incision phacoemulsification, intraocular lens implant, and trabeculectomy with intraoperative Mitomycin-C provide good intermediate range (1 year) postoperative IOP in eyes with coexisting cataract and glaucoma. In addition, small-incision surgery results in earlier and better visual rehabilitation than large-incision surgery.
比较在白内障超声乳化吸除联合人工晶状体植入及小梁切除术并术中应用丝裂霉素C时,3.2毫米切口与6.0毫米切口的手术效果。
45例转诊患者的57只患眼接受了白内障超声乳化吸除联合人工晶状体植入及小梁切除术并术中应用丝裂霉素C。前24只眼采用6.0毫米切口,后33只眼采用3.2毫米切口;其他手术步骤相同。对术后1天、1周、1个月和1年时的眼压、抗青光眼药物使用数量、滤过泡情况、视力及并发症进行多变量分析。
在任何术后随访时间点,两组间眼压控制情况、抗青光眼药物使用数量或滤过泡情况均无统计学差异。在整个评估期内,3.2毫米切口组的视力明显更好(p = 0.02)。
对于同时患有白内障和青光眼的患者,大切口和小切口的白内障超声乳化吸除联合人工晶状体植入及小梁切除术并术中应用丝裂霉素C均能在术后1年的中期范围内提供良好的眼压控制。此外,小切口手术比大切口手术能带来更早且更好的视力恢复。