两名肾病综合征患儿发生耐青霉素肺炎链球菌所致严重感染。

Serious infections due to penicillin-resistant Streptococcus peneumoniae in two children with nephrotic syndrome.

作者信息

Ilyas M, Roy S, Abbasi S, Leggiadro R J, English B K, Wyatt R J

机构信息

Department of Pediatrics, University of Tennessee, Memphis, USA.

出版信息

Pediatr Nephrol. 1996 Oct;10(5):639-41. doi: 10.1007/s004670050179.

DOI:10.1007/s004670050179

PMID:8897574

Abstract

Children with nephrotic syndrome are susceptible to the development of invasive bacterial infections, particularly those caused by Streptococcus peneumoniae. Recently, penicillin-resistant pneumococcal infections in children have occurred in increased frequency in some regions. We have seen two children with nephrotic syndrome who developed penicillin-resistant pneumococcal bacteremia and/or peritonitis. A change in the initial therapy from penicillin in the usual dose in these patients must be considered.

摘要

肾病综合征患儿易发生侵袭性细菌感染，尤其是由肺炎链球菌引起的感染。最近，儿童耐青霉素肺炎球菌感染在一些地区的发生率有所增加。我们见过两名肾病综合征患儿发生了耐青霉素肺炎球菌菌血症和/或腹膜炎。必须考虑对这些患者的初始治疗从常规剂量青霉素进行调整。