Kumagai S, Kusaka Y, Goto S
Department of Occupational Health, Osaka Prefectural Institute of Public Health, Japan.
Am Ind Hyg Assoc J. 1996 Apr;57(4):365-9. doi: 10.1080/15428119691014909.
Cobalt, used as a binder for tungsten carbide, has been demonstrated to be toxic to the lung and to be a sensitizer of the bronchial airways among hard metal workers. To determine cobalt exposure levels in 9 job groups at a hard metal factory, 935 samples were collected from 356 workers. The arithmetic means of 8-hr time-weighted averages were more than 50 micrograms/m3 (American Conference of Governmental Industrial Hygienists' threshold limit value) in the powder preparation, rubber press, and shaping groups. The within-worker and between-worker components of exposure variation were estimated for each job group using the random effects analysis-of-variance model. The geometric standard deviations indicating the within-worker and between-worker components ranged from 1.88 to 2.77 and 1.00 to 2.31, respectively.
钴作为碳化钨的粘结剂，已被证明对肺部有毒，并且在硬质合金工人中是支气管气道的致敏剂。为了确定一家硬质合金工厂9个工作岗位组的钴暴露水平，从356名工人中采集了935个样本。在粉末制备、橡胶压制和成型组中，8小时时间加权平均浓度的算术平均值超过了50微克/立方米（美国政府工业卫生学家会议的阈限值）。使用随机效应方差分析模型估计了每个工作岗位组暴露变异的工人内和工人间成分。表明工人内和工人间成分的几何标准差分别在1.88至2.77和1.00至2.31之间。
