Contant C M, van Geel A N, van der Holt B, Wiggers T
Department of Surgical Oncology, Academic Hospital Rotterdam-Dr. Daniel den Hoed Cancer Center, The Netherlands.
Eur J Surg Oncol. 1996 Oct;22(5):532-7. doi: 10.1016/s0748-7983(96)93143-1.
The aim of this study was to evaluate retrospectively the results of pedicled omentoplasty and split skin graft (POSSG) in reconstructing (full thickness) chest wall defects, and to define its role as a palliative procedure for local symptom control. Thirty-four patients with recurrent breast cancer (n = 25), radiation-induced necrosis (n = 5) or sarcoma (n = 4) of the chest wall were selected for the study. All patients underwent curative or palliative chest wall resection with reconstruction by pedicled omentoplasty and split skin graft (POSSG), between 1986 and 1994. Reconstructive outcome, complications, local tumour and symptom control following surgery was measured. The most common complication was shown to be partial necrosis of the omental flap (35%), followed by respiratory problems (26%), facial hernia (26%) and thoracic wound problems (15%), which were mostly treated in a conservative way (68%). The 3-year local tumour-free interval after POSSG in patients curatively treated for breast cancer is 16%. Seventy per cent of the patients who underwent palliative resection had longstanding relief of local pain, bleeding or foetor due to local tumour growth. It can be concluded that large (full thickness) chest wall defects after resection of local recurrence, primary malignancy or osteoradionecrosis of the chest wall can successfully be reconstructed by POSSG. Chest wall resection in patients treated with palliative intention is effective in local symptom control.
本研究旨在回顾性评估带蒂大网膜成形术联合中厚皮片移植术(POSSG)修复(全层)胸壁缺损的效果,并明确其作为缓解局部症状的姑息性手术的作用。本研究选取了34例胸壁复发性乳腺癌(n = 25)、放射性坏死(n = 5)或肉瘤(n = 4)患者。1986年至1994年间,所有患者均接受了根治性或姑息性胸壁切除术,并采用带蒂大网膜成形术联合中厚皮片移植术(POSSG)进行重建。测量了术后的重建效果、并发症、局部肿瘤及症状控制情况。最常见的并发症为大网膜瓣部分坏死(35%),其次为呼吸问题(26%)、面部疝(26%)和胸部伤口问题(15%),大多数并发症采用保守治疗(68%)。接受乳腺癌根治性治疗的患者在POSSG术后3年的局部无瘤间期为16%。接受姑息性切除术的患者中,70%因局部肿瘤生长导致的局部疼痛、出血或恶臭得到了长期缓解。可以得出结论,局部复发、原发性恶性肿瘤或胸壁骨放射性坏死切除术后的大面积(全层)胸壁缺损可通过POSSG成功修复。以姑息为目的进行胸壁切除术对局部症状控制有效。