Attias J, Bresloff I
Institute of Clinical Neurophysiology and Audiology, Schneider Children's Medical Center of Israel Petah Tikvah, Israel.
J Basic Clin Physiol Pharmacol. 1996;7(3):221-33. doi: 10.1515/jbcpp.1996.7.3.221.
Otoacoustic emissions are considered to reflect the outer hair cell activity of the cochlea, which in turn is recognised as the site most affected by noise exposure. The purpose of this study was to assess temporary cochlear alterations following brief noise exposure. Twenty young male subjects were exposed to 10 minutes of white noise at 90 dB SL. Standard pure tone audiometry, along with click and distortion product otoacoustic emissions (CEOAEs and DPOAEs), were measured before and after the noise exposure. Auditory pure tone threshold shifts of the order of 15 dB were accompanied by temporary CEOAE shifts of the order of 3 dB. DPOAE thresholds were elevated by approximately 5 dB. A positive, significant, and relatively strong correlation was obtained between the CEOAE shifts and the pure tone temporary threshold shifts (TTSs). However, in a number of cases emission shifts were unaccompanied by notable TTSs. Emissions appear to be more sensitive to cochlear changes following noise exposure and therefore more appropriate for screening and monitoring ears at risk of noise induced hearing loss (NIHL). The objectivity of the measurements and the short test time required further enhance their usefulness as a cochlear measure.
耳声发射被认为可反映耳蜗外毛细胞的活动,而耳蜗外毛细胞又被公认为是受噪声暴露影响最严重的部位。本研究的目的是评估短暂噪声暴露后耳蜗的暂时性改变。20名年轻男性受试者暴露于90 dB SL的白噪声中10分钟。在噪声暴露前后测量标准纯音听力测定以及短声和畸变产物耳声发射(CEOAEs和DPOAEs)。约15 dB的听觉纯音阈值变化伴随着约3 dB的暂时性CEOAEs变化。DPOAE阈值升高了约5 dB。CEOAEs变化与纯音暂时性阈值变化(TTSs)之间存在正相关、显著且相对较强的相关性。然而,在一些情况下,发射变化并未伴随明显的TTSs。耳声发射似乎对噪声暴露后耳蜗的变化更敏感,因此更适合用于筛查和监测有噪声性听力损失(NIHL)风险的耳朵。测量的客观性以及所需的短测试时间进一步提高了它们作为耳蜗测量指标的实用性。