Rudolph K K, Pasternak T
Department of Brain and Cognitive Science, University of Rochester, NY 14642, USA.
Cereb Cortex. 1996 Nov-Dec;6(6):814-22. doi: 10.1093/cercor/6.6.814.
We examined the effects of bilateral ibotenic acid lesions of cat lateral suprasylvian (LS) cortex on motion perception. Cats were tested on tasks requiring integration of local directional signals, precise judgements of direction and extraction of structure-from-motion. All animals showed permanent deficits in integrating local motion signals. These deficits were most pronounced in the presence of directional noise and at larger spatial displacements. In addition, LS lesions produced a 2-fold loss in the accuracy of direction discrimination and large deficits in the perception of structure-from-motion. All of these losses were most severe during the first few weeks of testing following the lesion. These findings demonstrate that LS cortex plays an important role in the processing of stimuli requiring integration of motion information and limits the spatial scale over which such integration can proceed. Partial improvements in performance with time and/or training may be indicative of post-operative plastic changes in neurons outside of LS cortex.
我们研究了猫外侧上薛氏回（LS）皮质双侧注射鹅膏蕈氨酸损伤对运动感知的影响。对猫进行了需要整合局部方向信号、精确方向判断以及从运动中提取结构的任务测试。所有动物在整合局部运动信号方面均表现出永久性缺陷。这些缺陷在存在方向噪声和较大空间位移时最为明显。此外，LS损伤使方向辨别准确性降低了两倍，并在从运动中感知结构方面出现了较大缺陷。所有这些损伤在损伤后的最初几周测试期间最为严重。这些发现表明，LS皮质在处理需要整合运动信息的刺激方面发挥着重要作用，并限制了这种整合能够进行的空间尺度。随着时间推移和/或训练，表现的部分改善可能表明LS皮质外的神经元发生了术后可塑性变化。
