一种用于测定市售氯化度米芬纯度的核磁共振方法。
A nuclear magnetic resonance method for the determination of the purity of commercial dequalinium chloride.
作者信息
Boschetti C, Fronza G, Fuganti C, Grasselli P, Magnone A G, Mele A, Pellegatta C
机构信息
Dipartimento di Chimica, Centro sullo Studio delle Sostanze Organiche Naturali, Milan, Italy.
出版信息
Arzneimittelforschung. 1995 Nov;45(11):1217-21.
PMID:8929243
Abstract
4-amino-1-(10-4'-quinaldinylaminodecyl)quinaldinium chloride (3) has been identified through nuclear magnetic resonance (NMR) studies as one of the impurities of a commercial sample of dequalinium chloride (CAS 522-51-0). The NMR technique is proposed as a rapid method for the recognition and quantification of the impurities in dequalinium chloride samples.
摘要
通过核磁共振（NMR）研究已确定4-氨基-1-（10-4'-喹哪啶基氨基癸基）喹哪啶鎓氯化物（3）是商品级氯化喹那啶（CAS 522-51-0）样品中的杂质之一。提出将NMR技术作为识别和定量氯化喹那啶样品中杂质的快速方法。
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