MacGillivray D C, Mumtaz M A, Kurtzman S H, Spencer R P, Weiner R E, Malchoff C D
Department of Surgery, University of Connecticut Health Center, Farmington, USA.
Arch Surg. 1996 Dec;131(12):1338-42. doi: 10.1001/archsurg.1996.01430240092013.
Somatostatin-receptor imaging is an effective method for localizing and staging neuroendocrine tumors. We describe patients with gastroenteropancreatic endocrine tumors who underwent preoperative indium In 111 pentetreotide scintigraphy. In 3 patients without prior resections, the results of a 111In pentetreotide scan were positive because of unsuspected regional lymph node metastases without localization of the primary tumors. In these patients, an extensive intraoperative search was required to identify the primary tumors, despite the positive preoperative scan results. In a fourth patient, who had previously undergone resection of a duodenal gastrinoma, 2 regional nodal metastases were identified by a 111In pentetreotide scan.
生长抑素受体显像术是一种定位和分期神经内分泌肿瘤的有效方法。我们描述了接受术前铟 In 111 喷曲肽闪烁扫描的胃肠胰内分泌肿瘤患者。在 3 例未经先前切除的患者中，由于未被怀疑的区域淋巴结转移而无原发性肿瘤定位，铟 In 111 喷曲肽扫描结果呈阳性。在这些患者中，尽管术前扫描结果呈阳性，但仍需要在术中进行广泛探查以确定原发性肿瘤。在第 4 例患者中，该患者先前已切除十二指肠胃泌素瘤，铟 In 111 喷曲肽扫描发现了 2 个区域淋巴结转移。
