Ono R
Department of Endoscopy, National Cancer Center Hospital.
Nihon Rinsho. 1996 May;54(5):1337-42.
We have recently developed bronchoscopic brachytherapy as a new modality for treating tracheal and bronchial malignancies, and have assessed the feasibility of bronchoscopic ultrasonic diagnosis and bronchoscopic brachytherapy for tracheal and bronchial malignant diseases, using a combination of videobronchoscope, an ultrasonic probe and a high-dose-rate Microselectron. Between September 1992 and December 1994, 34 patients having a total of 34 lesions of the trachea and bronchus received bronchoscopic brachytherapy at the National Cancer Center Hospital. In all 34 of these cases lung cancer was histologically confirmed by biopsy before treatment, although these cancer lesions were roentgenographically occult. Of the 34 patients who received bronchoscopic brachytherapy, 33 patients showed complete response to this therapy. Although 4 patients died of other diseases, the 3-year survival rate was 88.6%. The results of our study show that in such cases bronchoscopic brachytherapy yields a high rate of therapeutic response.
我们最近开发了支气管镜近距离放射疗法，作为治疗气管和支气管恶性肿瘤的一种新方法，并使用视频支气管镜、超声探头和高剂量率微型后装治疗机的组合，评估了支气管镜超声诊断和支气管镜近距离放射疗法对气管和支气管恶性疾病的可行性。在1992年9月至1994年12月期间，34例共有34处气管和支气管病变的患者在国立癌症中心医院接受了支气管镜近距离放射疗法。在所有这34例病例中，尽管这些癌症病变在X线片上隐匿，但在治疗前经活检在组织学上确诊为肺癌。在接受支气管镜近距离放射疗法的34例患者中，33例对该疗法显示出完全缓解。虽然有4例患者死于其他疾病，但3年生存率为88.6%。我们的研究结果表明，在这类病例中，支气管镜近距离放射疗法产生了很高的治疗反应率。
