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POU domain factors of the Brn-3 class recognize functional DNA elements which are distinctive, symmetrical, and highly conserved in evolution.
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POU-specific domain of Oct-2 factor confers 'octamer' motif DNA binding specificity on heterologous Antennapedia homeodomain.
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Solution structure of the Oct-1 POU homeodomain determined by NMR and restrained molecular dynamics.
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Combinatorial activation and repression by seven transcription factors specify Drosophila odorant receptor expression.
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Abnormal chemosensory jump 6 is a positive transcriptional regulator of the cholinergic gene locus in Drosophila olfactory neurons.
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Essential role of POU-domain factor Brn-3c in auditory and vestibular hair cell development.
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A novel genetic system to isolate a dominant negative effector on DNA-binding activity of Oct-2.
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POU domain factors of the Brn-3 class recognize functional DNA elements which are distinctive, symmetrical, and highly conserved in evolution.
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本文引用的文献
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Expression domains of the Cf1a POU domain protein during Drosophila development.
Rouxs Arch Dev Biol. 1995 Aug;204(7-8):502-508. doi: 10.1007/BF00360858.
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Brn-3.0 expression identifies early post-mitotic CNS neurons and sensory neural precursors.
Mech Dev. 1995 Nov;53(3):291-304. doi: 10.1016/0925-4773(95)00435-1.
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Role of transcription factors Brn-3.1 and Brn-3.2 in auditory and visual system development.
Nature. 1996 Jun 13;381(6583):603-6. doi: 10.1038/381603a0.
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POU domain factor Brn-3b is required for the development of a large set of retinal ganglion cells.
Proc Natl Acad Sci U S A. 1996 Apr 30;93(9):3920-5. doi: 10.1073/pnas.93.9.3920.
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Development and survival of the endocrine hypothalamus and posterior pituitary gland requires the neuronal POU domain factor Brn-2.
Genes Dev. 1995 Dec 15;9(24):3122-35. doi: 10.1101/gad.9.24.3122.
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The POU domain transcription factor Brn-2 is required for the determination of specific neuronal lineages in the hypothalamus of the mouse.
Genes Dev. 1995 Dec 15;9(24):3109-21. doi: 10.1101/gad.9.24.3109.
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Mad: a heterodimeric partner for Max that antagonizes Myc transcriptional activity.
Cell. 1993 Jan 29;72(2):211-22. doi: 10.1016/0092-8674(93)90661-9.
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Tissue-specific RNA splicing generates an ankyrin-like domain that affects the dimerization and DNA-binding properties of a bHLH protein.
Genes Dev. 1993 Jan;7(1):55-71. doi: 10.1101/gad.7.1.55.
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Brn-3.0: a POU-domain protein expressed in the sensory, immune, and endocrine systems that functions on elements distinct from known octamer motifs.
Proc Natl Acad Sci U S A. 1993 Nov 15;90(22):10841-5. doi: 10.1073/pnas.90.22.10841.
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Crystal structure of the Oct-1 POU domain bound to an octamer site: DNA recognition with tethered DNA-binding modules.
Cell. 1994 Apr 8;77(1):21-32. doi: 10.1016/0092-8674(94)90231-3.
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