Spiel R, Enenkel W, Fischer M
Z Kardiol. 1977 Jul;66(7):402-4.
A case of agranulocytosis (min. leucocyte count 980/mm3) after 4 weeks of treatment with an ajmalin derivate is reported. Recovery could be achieved by taking away the antiarrhythmic drug. It appears that these agranulocytoses only happen after a dosage of more than 300 mg/die, and that they have an intermediate position between allergic and toxic agranulocytosis (phenothiazine type).
报告了1例在用阿马林衍生物治疗4周后出现粒细胞缺乏症(最低白细胞计数为980/mm³)的病例。停用抗心律失常药物后病情得以恢复。似乎这些粒细胞缺乏症仅在剂量超过300mg/日时发生,且它们在过敏性和中毒性粒细胞缺乏症(吩噻嗪类)之间处于中间位置。