Hayashi J, Eguchi S, Yasuda K, Komatsu S, Tabayashi K, Masuda M, Yozu R, Amemiya K, Takeuchi E, Nakano S, Adachi S, Matsuo H, Takamiya M
Niigata University School of Medicine, Niigata, Japan.
Ann Thorac Surg. 1997 Jan;63(1):93-7. doi: 10.1016/s0003-4975(96)01060-0.
Little is known about the risks of mortality and morbidity after descending thoracic aortic aneurysm repair using left heart bypass and temporary arterioarterial bypass.
A multicenter, retrospective study was performed on 120 patients who were admitted to one of nine cardiovascular centers between January 1988 and December 1993 and underwent operation for nondissecting thoracic aortic aneurysm. The present series included 10 patients with ruptured aneurysm. Graft replacement was performed in 95 patients, patch repair in 22, and suture of the ruptured aorta in 3. Venoarterial bypass was used in 45 patients, left heart bypass in 56, and temporary arterioarterial bypass in 19 as circulatory support. The mean postoperative follow-up period was 30 +/- 21 months.
Hospital mortality occurred in 7 patients (5.8%). Univariate analysis revealed that only aneurysmal rupture was related to hospital mortality. Brain or cord injury was observed in 4. Of nine deaths that occurred after discharge, five were related to aneurysm and two were due to vascular event. No significant difference was noticed in probability of survival according to the circulatory supporting method. Only aneurysmal rupture affected probability of survival. Multivariate analysis revealed that aneurysmal rupture was the only independent predictor for vascular death including hospital mortality.
The present study confirms that aneurysmal rupture is a significant predictor for mortality and morbidity in aortic operations for nondissecting descending thoracic aneurysm, and that a similarly good outcome would be expected when using left heart bypass, temporary arterioarterial bypass, or venoarterial bypass.
关于采用左心转流和临时动脉-动脉转流术修复降胸主动脉瘤后死亡和发病风险的了解甚少。
对1988年1月至1993年12月期间入住9个心血管中心之一并接受非夹层胸主动脉瘤手术的120例患者进行了一项多中心回顾性研究。本系列包括10例动脉瘤破裂患者。95例行人工血管置换术,22例行补片修补术,3例行破裂主动脉缝合术。45例患者使用静脉-动脉转流,56例使用左心转流,19例使用临时动脉-动脉转流作为循环支持。术后平均随访时间为30±21个月。
7例(5.8%)患者发生医院死亡。单因素分析显示,仅动脉瘤破裂与医院死亡相关。观察到4例脑或脊髓损伤。出院后发生的9例死亡中,5例与动脉瘤有关,2例因血管事件死亡。根据循环支持方法,生存率无显著差异。仅动脉瘤破裂影响生存率。多因素分析显示,动脉瘤破裂是包括医院死亡在内的血管死亡的唯一独立预测因素。
本研究证实,动脉瘤破裂是降胸主动脉非夹层动脉瘤手术中死亡和发病的重要预测因素,并且使用左心转流、临时动脉-动脉转流或静脉-动脉转流时预期会有相似的良好结果。