Wulff J, Lönn U, Keck K Y, Wranne B, Ask P, Peterzén B, Casimir-Ahn H
Department of Cardiothoracic Anesthesiology, Linköping Heart Center, University of Linköping, Sweden.
Ann Thorac Surg. 1997 Jan;63(1):162-6. doi: 10.1016/s0003-4975(96)00746-1.
The Hemopump (DLP/Medtronic) has been in clinical use for about 7 years. There is still no adequate way of determining actual output from the three available pump systems in the clinical situation. If the pump is completely stopped during weaning from the device, there is a possibility of back-leakage through the pump, endangering the patient from regurgitation into the left ventricle. It can also make it more difficult to judge the recovery of heart function because of a volume load of the left ventricle. The aim of this study was to evaluate in a standardized, experimental in vitro model the output from three different-sized Hemopump catheters at various pressure levels and to quantify the back-flow through the pumps.
The Hemopump models were tested in an in vitro study regarding total outflow at various speeds at three pressure levels. The back-flow through the pumps was also measured with the pumps at a complete stop.
The outflow from the Hemopumps ranged from 0.4 to 4.5 L/min, depending on which pump and speed were used. Variations in total output, depending on speed and various pressure settings, could be up to 0.4 L/min. Back-flow through the pump into the left ventricle may be as great as 1.6 L/min.
The flow outputs from the different Hemopump models were reproducible over time and were closely related to the resistance of the model. The Hemopump, if not running, can induce substantial regurgitation through the pump into the left ventricle.
Hemopump（DLP/美敦力公司）已临床应用约7年。在临床情况下，仍没有足够的方法来确定三种可用泵系统的实际输出量。如果在撤机过程中泵完全停止，存在血液通过泵逆流的可能性，这会使患者面临左心室反流的危险。由于左心室的容量负荷，这也会使判断心脏功能的恢复更加困难。本研究的目的是在标准化的体外实验模型中，评估三种不同尺寸的Hemopump导管在不同压力水平下的输出量，并对通过泵的逆流进行量化。
在体外研究中，对Hemopump模型在三种压力水平下不同速度时的总流出量进行测试。同时在泵完全停止时测量通过泵的逆流情况。
Hemopump的流出量在0.4至4.5升/分钟之间，具体取决于所使用的泵和速度。根据速度和各种压力设置，总输出量的变化可能高达0.4升/分钟。通过泵逆流回左心室的量可能高达1.6升/分钟。
不同Hemopump模型的流量输出随时间具有可重复性，并且与模型的阻力密切相关。Hemopump如果不运行，会导致大量血液通过泵逆流回左心室。
