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骶后根切断术及硬膜内骶前根刺激术治疗脊髓损伤患者的痉挛性膀胱

Posterior sacral rhizotomy and intradural anterior sacral root stimulation for treatment of the spastic bladder in spinal cord injured patients.

作者信息

Schurch B, Rodic B, Jeanmonod D

机构信息

Swiss Paraplegic Centre, University Balgrist, Switzerland.

出版信息

J Urol. 1997 Feb;157(2):610-4.

PMID:8996369
Abstract

PURPOSE

The efficacy of intradural sacral posterior rhizotomy combined with intradural sacral anterior root stimulation in the treatment of the neurogenic hyperreflexic bladder was evaluated.

MATERIALS AND METHODS

We reviewed 10 spinal cord injured patients who underwent surgery between September 1990 and February 1994. Bladder function was compared preoperatively and postoperatively. Intraoperative data on electrostimulation of the detrusor and striated muscles were analyzed.

RESULTS

Stimulation of the anterior S3 and S4 roots was mostly used to empty the bladder (7 of 10 cases). Preoperative reflex incontinence disappeared in all patients postoperatively. Mean postoperative bladder capacity increases and mean postoperative post-void residual decreases were at least 340 ml. (p < 0.01) and 140 ml. (p < 0.01), respectively. Preoperative vesicorenal reflux disappeared in 2 and improved in 3 cases after sacral deafferentation. Autonomic hyperreflexia, which was present preoperatively in 6 patients, never disappeared but significantly improved after deafferentation. No major complications were noted postoperatively.

CONCLUSIONS

Intradural sacral posterior rhizotomy combined with intradural sacral anterior root stimulation is a valuable method to treat the hyperreflexic bladder with incontinence resistant to conservative therapy in spinal cord injured patients. Autonomic hyperreflexia was decreased but not suppressed by posterior sacral rhizotomy.

摘要

目的

评估硬膜内骶后根切断术联合硬膜内骶前根刺激术治疗神经源性反射亢进膀胱的疗效。

材料与方法

我们回顾了1990年9月至1994年2月间接受手术的10例脊髓损伤患者。比较术前和术后的膀胱功能。分析术中逼尿肌和横纹肌电刺激的数据。

结果

刺激S3和S4前根大多用于排空膀胱(10例中的7例)。所有患者术后术前的反射性尿失禁均消失。术后平均膀胱容量增加至少340毫升(p<0.01),术后平均残余尿量减少至少140毫升(p<0.01)。骶去传入神经后,术前存在的膀胱输尿管反流2例消失,3例改善。术前6例患者存在的自主神经反射亢进从未消失,但去传入神经后明显改善。术后未发现重大并发症。

结论

硬膜内骶后根切断术联合硬膜内骶前根刺激术是治疗脊髓损伤患者中对保守治疗耐药的反射亢进性膀胱伴尿失禁的一种有价值的方法。骶后根切断术可降低但不能抑制自主神经反射亢进。

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