Colonoscopic excision of large sessile polyps.

Experience with 80 consecutively-encountered large sessile colon polypoid lesions is reviewed in order to document the salient principles involved with safe and total endoscopic excision of certain of these lesions. The endoscopic physical characteristics of the polypoid lesion is the single most important factor in determining the method of removal of sessile polypoid lesions. Considerable experience with diagnostic colonoscopy and endoscopic removal of pedunculated and small sessile lesions is most important before considering the technic of piece-meal polypectomy for large sessile benign lesions.