在产生庆大霉素和新霉素的放线菌中，涉及酮式和氨基肌醇以及谷氨酰胺的转氨作用。 - Suppr

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超能文献

Transaminations involving keto- and amino-inositols and glutamine in Actinomycetes which produce gentamicin and neomycin.

作者信息

Chen Y M, Walker J B

出版信息

Biochem Biophys Res Commun. 1977 Jul 25;77(2):688-92. doi: 10.1016/s0006-291x(77)80033-8.

DOI:10.1016/s0006-291x(77)80033-8

PMID:901497

Abstract

摘要

相似文献

Transaminations involving keto- and amino-inositols and glutamine in Actinomycetes which produce gentamicin and neomycin.在产生庆大霉素和新霉素的放线菌中，涉及酮式和氨基肌醇以及谷氨酰胺的转氨作用。

Biochem Biophys Res Commun. 1977 Jul 25;77(2):688-92. doi: 10.1016/s0006-291x(77)80033-8.

Levels of certain intermediary enzymes in gentamicin production by Micromonospora purpurea.紫色小单孢菌生产庆大霉素过程中某些中间酶的水平。

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Reactions catalyzed by purified L-glutamine: keto-scyllo-inositol aminotransferase, an enzyme required for biosynthesis of aminocyclitol antibiotics.由纯化的L-谷氨酰胺：酮基-scyllo-肌醇氨基转移酶催化的反应，该酶是氨基环醇类抗生素生物合成所必需的一种酶。

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Isolation and characterisation of an aminoglycoside phosphotransferase from neomycin-producing Micromonospora chalcea; comparison with that of Streptomyces fradiae and other producers of 4,6-disubstituted 2-deoxystreptamine antibiotics.从新霉素产生菌铜色小单孢菌中分离和鉴定一种氨基糖苷磷酸转移酶；与弗氏链霉菌及其他4,6-二取代2-脱氧链霉胺类抗生素产生菌的该酶进行比较。

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Functional characterization of kanB by complementing in engineered Streptomyces fradiae Deltaneo6::tsr.通过在工程改造的弗氏链霉菌Deltaneo6::tsr中进行互补来对kanB进行功能表征。

Biotechnol Lett. 2009 Jun;31(6):869-75. doi: 10.1007/s10529-009-9937-0. Epub 2009 Feb 15.

Aminoglycoside-modifying enzymes.氨基糖苷类修饰酶

Methods Enzymol. 1975;43:611-28. doi: 10.1016/0076-6879(75)43124-x.

L-glutamine:keto-scyllo-inositol aminotransferase.L-谷氨酰胺：酮基-scyllo-肌醇氨基转移酶

Methods Enzymol. 1975;43:439-43. doi: 10.1016/0076-6879(75)43099-3.

Aminoglycoside antibiotic-inactivating enzymes in actinomycetes similar to those present in clinical isolates of antibiotic-resistant bacteria.放线菌中与耐药临床分离菌中存在的那些酶类似的氨基糖苷类抗生素失活酶。

Proc Natl Acad Sci U S A. 1973 Aug;70(8):2276-80. doi: 10.1073/pnas.70.8.2276.

The three-dimensional structure of NeoB: An aminotransferase involved in the biosynthesis of neomycin.NeoB 的三维结构：参与新霉素生物合成的氨基转移酶。

Protein Sci. 2018 May;27(5):945-956. doi: 10.1002/pro.3400. Epub 2018 Apr 2.

Transcriptional mapping of the promoter of the aminoglycoside acetyltransferase gene (aacC9) of neomycin-producing Micromonospora chalcea.新霉素产生菌铜绿小单孢菌氨基糖苷乙酰转移酶基因（aacC9）启动子的转录图谱分析

Res Microbiol. 1992 Feb;143(2):133-8. doi: 10.1016/0923-2508(92)90002-6.

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Biochimie. 2009 Sep;91(9):1072-80. doi: 10.1016/j.biochi.2009.07.003. Epub 2009 Jul 10.

Enzymatic synthesis of aminoglycoside antibiotics: novel adenosylmethionine:2-deoxystreptamine N-methyltransferase activities in hygromycin B- and spectinomycin-producing Streptomyces spp. and uses of the methylated products.氨基糖苷类抗生素的酶促合成：潮霉素B和壮观霉素产生链霉菌属中新型腺苷甲硫氨酸：2-脱氧链霉胺N-甲基转移酶活性及甲基化产物的用途。

Appl Environ Microbiol. 2002 May;68(5):2404-10. doi: 10.1128/AEM.68.5.2404-2410.2002.

Enzymatic synthesis of aminocyclitol moieties of aminoglycoside antibiotics from inositol by Streptomyces spp.: detection of glutamine-aminocyclitol aminotransferase and diaminocyclitol aminotransferase activities in a spectinomycin producer.链霉菌属细菌从肌醇酶促合成氨基糖苷类抗生素的氨基环醇部分：在壮观霉素产生菌中检测谷氨酰胺-氨基环醇氨基转移酶和二氨基环醇氨基转移酶活性

J Bacteriol. 1995 Feb;177(3):818-22. doi: 10.1128/jb.177.3.818-822.1995.

Isolation of streptomycin-nonproducing mutants deficient in biosynthesis of the streptidine moiety or linkage between streptidine 6-phosphate and dihydrostreptose.分离在链霉胍部分生物合成或磷酸链霉胍与二氢链霉糖之间的连接方面存在缺陷的不产生链霉素的突变体。

Antimicrob Agents Chemother. 1985 Mar;27(3):367-74. doi: 10.1128/AAC.27.3.367.

Antimicrob Agents Chemother. 1989 Apr;33(4):452-9. doi: 10.1128/AAC.33.4.452.

On the development of enzymic pathways for the biosynthesis of aminocyclitol antibiotics and other idiolites.关于氨基环醇类抗生素及其他特殊化合物生物合成酶途径的发展。

Folia Microbiol (Praha). 1979;24(3):286-91. doi: 10.1007/BF02926462.

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