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深部颈部间隙感染的现代管理

Contemporary management of deep neck space infections.

作者信息

Gidley P W, Ghorayeb B Y, Stiernberg C M

机构信息

Department of Otolaryngology-Head and Neck Surgery, University of Texas Medical School at Houston, USA.

出版信息

Otolaryngol Head Neck Surg. 1997 Jan;116(1):16-22. doi: 10.1016/s0194-5998(97)70345-0.

Abstract

Deep neck infections continue to be seen despite the wide use of antibiotics. These infections follow along fascial planes to create deep neck space abscesses. The clinical presentation often points to the space involved. Understanding the regional anatomy gives the surgeon the ability to treat these grave infections. The records of 24 patients with a diagnosis of deep neck space abscess admitted to Hermann Hospital between 1988 and 1993 were reviewed. Fifty percent of the patients had received antibiotics for an infection of the ear, nose, or throat before the development of a neck space abscess. Ten patients had parapharyngeal abscesses, seven had retropharyngeal abscesses, six had submandibular space abscesses, and one had parotid space abscess. Thirty-five organisms were isolated in 18 cases (1.9 isolates per patient). The most common organism cultured was Streptococcus (13 of 18), followed by Staphylococcus (6 of 18), Bacteroides (5 of 18), Micrococcus (2 of 18), and Neisseria (2 of 18). One case each of Candida, Enterobacter, Enterococcus, Peptostreptococcus, Proteus, Proprionobacter, and Pseudomonas was cultured. Six patients had no growth on culture but did have organisms found on Gram's stain. The operative techniques and antibiotics used are discussed. The main complications of jugular vein thrombosis, carotid artery rupture, and mediastinitis are described, as well as an unusual case of meningitis from a large retropharyngeal-parapharyngeal abscess.

摘要

尽管抗生素被广泛使用,但深部颈部感染仍时有发生。这些感染沿着筋膜平面发展,形成深部颈部间隙脓肿。临床表现往往提示受累间隙。了解局部解剖结构有助于外科医生治疗这些严重感染。回顾了1988年至1993年间入住赫尔曼医院的24例诊断为深部颈部间隙脓肿患者的病历。50%的患者在颈部间隙脓肿形成前曾因耳、鼻或喉感染接受过抗生素治疗。10例患者患有咽旁脓肿,7例患有咽后脓肿,6例患有颌下间隙脓肿,1例患有腮腺间隙脓肿。18例患者分离出35种微生物(平均每位患者分离出1.9种)。培养出的最常见微生物是链球菌(18例中的13例),其次是葡萄球菌(18例中的6例)、拟杆菌(18例中的5例)、微球菌(18例中的2例)和奈瑟菌(18例中的2例)。念珠菌、肠杆菌、肠球菌、消化链球菌、变形杆菌、丙酸杆菌和假单胞菌各有1例培养出。6例患者培养无生长,但革兰氏染色发现有微生物。讨论了手术技术和使用的抗生素。描述了主要并发症,如颈静脉血栓形成、颈动脉破裂和纵隔炎,以及一例由巨大咽后-咽旁脓肿引起的不寻常脑膜炎病例。

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