Pobil Moreno J L, Martínez Rodríguez J, Maestro Durán J L, Morales López A
Servicio de Urología, Hospital Universitario Virgen del Rocío, Sevilla, España.
Arch Esp Urol. 1996 Sep;49(7):700-5.
To analyze the clinical and histological characteristics of 5 cases of Leydig cell tumor in order to establish the criteria for conservative surgical management.
Of 31 testicular tumors diagnosed from 1982-1993, 5(16.1%) were Leydig cell tumors. We analyzed patient general characteristics, the prevalent feminizing (60%) and hypogonadal features and the histopathological characteristics that might indicate a non aggressive course of the tumor.
No metastasis was observed at 522.9 months mean follow up. Three patients underwent orchidectomy through the inguinal approach; one case had been incidentally discovered after subalbuginea resection due to a disseminated prostatic carcinoma and the fifth patient was treated conservatively by tumorectomy and is tumor-free at more than 120 months follow up.
Parenchyma-sparing surgery may have a place in the treatment of interstitial cell tumor, with evident endocrinological and psychological benefits, especially in the young males that meet the clinical and histological criteria for conservative surgical management.