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[特异性治疗后血吸虫病肝纤维化的逆转。组织病理学研究]

[On the reversal of schistosomiasis hepatic fibrosis after specific therapy. Histopathologic study].

作者信息

Chapadeiro E, Pitanga L C

机构信息

Departamento de Patologia, Medicina Legal e do Curso de Pós-graduação em Patologia Humana da Faculdade de Medicina do Triângulo Mineiro, Uberaba, MG, Brasil.

出版信息

Rev Soc Bras Med Trop. 1997 Jan-Feb;30(1):53-6. doi: 10.1590/s0037-86821997000100010.

Abstract

Surgical liver biopsies of patients of both sexes, between 18 and 72 years old, with the compensated hepatoesplenic form of schistosomiasis mansoni, previously treated with oxaminique (Mansil) were studied by histological and immunohistochemical methods. Although the search for parasites and/or granulomas was negative in all specimen studied, the portal fibrosis remained.

摘要

对年龄在18至72岁之间、患有曼氏血吸虫病肝脾代偿型且先前接受过奥沙米尼克(曼西尔)治疗的男女患者进行了手术肝活检,采用组织学和免疫组织化学方法进行研究。尽管在所研究的所有标本中均未发现寄生虫和/或肉芽肿,但门静脉纤维化仍然存在。

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