Hurlé A, Nistal J F, Revuelta J M
Department of Cardiovascular Surgery, University Hospital Marqués de Valdecilla, School of Medicine, University of Santander, Spain.
Artif Organs. 1997 Feb;21(2):116-20. doi: 10.1111/j.1525-1594.1997.tb00347.x.
By January 1994, a total of 40 Wessex porcine bioprostheses (21 mitral, 18 aortic, and 1 tricuspid) were explanted from 31 subjects. They belonged to a series of 150 patients who received 184 of such prostheses in our unit. Seventeen of these explanted prostheses were available for study, and 11 of them presented some sort of stent fracture or fissuring (mean of 3.6 +/- 1.6 fractures per prosthesis). The disruption occurred in all cases at the base of the commissural arch or at the commissural bar of the stent. The fractures were not detected clinically nor echo-cardiographically before reoperation, and most valves were explanted for reasons other than the stent rupture itself. The actuarial probability of freedom from stent fracture in our series is 66 +/- 12% at 9 years of follow-up. In our experience, fracture of the stent is an important mode of structural dysfunction of the Wessex porcine bioprostheses.
到1994年1月,共从31名受试者体内取出40个韦塞克斯猪生物瓣膜(21个二尖瓣、18个主动脉瓣和1个三尖瓣)。它们属于在我们科室接受184个此类瓣膜的150例患者系列。其中17个取出的瓣膜可供研究,其中11个出现了某种支架断裂或裂开(每个瓣膜平均有3.6±1.6处断裂)。所有病例的破坏均发生在联合弓基部或支架的联合杆处。在再次手术前,临床及超声心动图检查均未发现这些断裂,且大多数瓣膜因支架破裂本身以外的原因被取出。在我们的系列研究中,随访9年时支架无断裂的精算概率为66±12%。根据我们的经验,支架断裂是韦塞克斯猪生物瓣膜结构功能障碍的一种重要方式。