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孔源性视网膜脱离术后增生性玻璃体视网膜病变的发生率是否降低了?

[Has the incidence of postoperative PVR in rhegmatogenous retinal detachment decreased?].

作者信息

Bonnet M, Guenoun S, Yaniali A, Fleury J, Hajjar C, Dumas C, Duquesne N, Semiglia R

机构信息

UFR Lyon Nord, Hôpital de la Croix-Rousse.

出版信息

J Fr Ophtalmol. 1996;19(11):696-704.

PMID:9033891
Abstract

PURPOSE

To determine whether the incidence of severe postoperative PVR in primary rhegmatogenous retinal detachment has decreased over the last twelve years.

MATERIALS AND METHODS

We prospectively evaluated 595 eyes of 554 consecutive patients with primary rhegmatogenous retinal detachment, referred before any failed attempt to reattach the retina, managed by the same surgeon between March 1983 and December 1994. The eyes were divided into two consecutive series: 275 eyes operated on from March 1983 through February 1988 (series no. 1), and 320 eyes operated on from February 1988 through December 1994 (series no. 2). We conducted univariate and multivariate statistical analyses to compare the incidence of postoperative PVR in the two consecutive series.

RESULTS

The overall incidence of postoperative PVR was 8.72% (24/275 eyes) in series no. 1, versus 2.81% (9/320 eyes) in series no. 2 (p < 0.01). The incidence of postoperative PVR in retinal detachments due to atrophic holes in lattice degeneration, oral dialyses, and macular holes in myopic eyes, was nil in both series. The incidence of postoperative PVR in retinal detachments due to horseshoe tears with mobile posterior edges was 1.16% (1/86 eyes) in series no. 1, and 0% (0/109 eyes) in series no. 2. The incidence of postoperative PVR in retinal detachments associated with horseshoe tears with curled posterior edges was 21.15% (11/52 eyes) in series no. 1 versus 3.2% (3/93 eyes) in series no. 2 (p < 0.001). The incidence of postoperative PVR in giant tears was 35.5% (11/31 eyes) in series no. 1. and 14.7% (5/34 eyes) in series no. 2 (chi square = 3.77; at the limit of significance). The incidence of postoperative PVR in retinal detachments du to paravascular tears of the post-equatorial region in myopic eyes was 25% (1/4 eyes) in series no. 1, and 14% (1/7 eyes) in series no. 2.

CONCLUSION

In our own experience, the incidence of postoperative PVR in primary rhegmatogenous retinal detachment has decreased at a statistically significant level since 1988. We believe that the decreased incidence of postoperative PVR in our most recent series is mainly related to the use of laser photocoagulation retinopexy rather than cryopexy in the management of high risk eyes (retinal detachments associated with horseshoe tears with curled posterior edges, and giant tears).

摘要

目的

确定在过去十二年中,原发性孔源性视网膜脱离术后严重增生性玻璃体视网膜病变(PVR)的发生率是否有所下降。

材料与方法

我们前瞻性评估了554例连续的原发性孔源性视网膜脱离患者的595只眼,这些患者在任何视网膜复位失败尝试之前前来就诊,于1983年3月至1994年12月由同一位外科医生进行治疗。这些眼睛被分为两个连续的系列:1983年3月至1988年2月手术的275只眼(系列1),以及1988年2月至1994年12月手术的320只眼(系列2)。我们进行了单变量和多变量统计分析,以比较两个连续系列中术后PVR的发生率。

结果

系列1中术后PVR的总体发生率为8.72%(24/275只眼),而系列2中为2.81%(9/320只眼)(p<0.01)。在格子样变性萎缩孔、视网膜锯齿缘离断和近视眼黄斑裂孔导致的视网膜脱离中,两个系列的术后PVR发生率均为零。马蹄形裂孔伴可移动后缘导致的视网膜脱离中,系列1的术后PVR发生率为1.16%(1/86只眼),系列2为0%(0/109只眼)。马蹄形裂孔伴卷曲后缘相关的视网膜脱离中,系列1的术后PVR发生率为21.15%(11/52只眼)而系列2为3.2%(3/93只眼)(p<0.001)。巨大裂孔的术后PVR发生率在系列1中为35.5%(11/31只眼),系列2中为14.7%(5/34只眼)(卡方检验=3.77;接近显著性界限)。近视眼赤道后区域血管旁裂孔导致的视网膜脱离中,系列1的术后PVR发生率为25%(1/4只眼),系列2为14%(1/7只眼)。

结论

根据我们自己的经验,自1988年以来,原发性孔源性视网膜脱离术后PVR的发生率在统计学上有显著下降。我们认为,在我们最近的系列中,术后PVR发生率的下降主要与在高危眼(马蹄形裂孔伴卷曲后缘和巨大裂孔相关的视网膜脱离)的治疗中使用激光光凝视网膜固定术而非冷冻疗法有关。

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