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失重对母胎系统的影响(国外“航天飞机”上NIH-R1胚胎学实验结果)

[Effect of weightlessness on the mother-fetus system (results of embryological experiment NIH-R1 abroad the "Space Shuttle"].

作者信息

Serova L V, Natochkin I V, Nosovskii A M, Shakhmatova E I, Fast T

机构信息

State Scientific Center RF "Institute of Medico-Biological Problems".

出版信息

Aviakosm Ekolog Med. 1996;30(6):4-8.

PMID:9035797
Abstract

Female rats were exposed to weightlessness in the mid-deck of US "Space Shuttle" in the period between days 9 to 20 of pregnancy and examined on Earth post flight. No significant structural anomalies threatening the life and normal development were found in newborn rats carried by mothers under the conditions of weightless exposures. Water, Na, K, Ca, Fe and Cu contents in fetal and placental tissues of the flight animals were not changed. Differences between the flight and ground-based synchronous controls, or the rates of formation of the fetal skeleton were not revealed. Comparison of these data with results of the experiment aboard biosatellite "Cosmos 1514" in which female rats stayed in weightlessness from day 13 to 18 of pregnancy indicates that the two-fold increase of space flight duration did not add changes in the state of fetuses.

摘要

雌性大鼠在妊娠第9至20天期间于美国“航天飞机”的中层甲板上暴露于失重环境,飞行后在地球上进行检查。在失重暴露条件下的母鼠所产新生大鼠中,未发现威胁生命和正常发育的明显结构异常。飞行动物的胎儿和胎盘组织中的水、钠、钾、钙、铁和铜含量未发生变化。未发现飞行组与地面同步对照组之间存在差异,也未发现胎儿骨骼形成速率存在差异。将这些数据与在生物卫星“宇宙1514”上进行的实验结果进行比较,在该实验中雌性大鼠在妊娠第13至18天处于失重状态,结果表明太空飞行持续时间增加两倍并未使胎儿状态产生更多变化。

相似文献

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[Effect of weightlessness on the mother-fetus system (results of embryological experiment NIH-R1 abroad the "Space Shuttle"].失重对母胎系统的影响(国外“航天飞机”上NIH-R1胚胎学实验结果)
Aviakosm Ekolog Med. 1996;30(6):4-8.
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