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大疱性肺气肿治疗的一种替代技术。胸腔镜下大疱内圈套结扎术。

An alternative technique in the management of bullous emphysema. Thoracoscopic endoloop ligation of bullae.

作者信息

Liu H P, Chang C H, Lin P J, Chu J J, Hsieh M J

机构信息

Department of Thoracic and Cardiovascular Surgery, Chang Gung Memorial Hospital, Chang Gung Medical College, Taipei, Taiwan, ROC.

出版信息

Chest. 1997 Feb;111(2):489-93. doi: 10.1378/chest.111.2.489.

Abstract

STUDY OBJECTIVES

With the improvements in video-assisted thoracoscopic surgery, more older patients and patients with respiratory impairments are undergoing bulla ablation using new and costly technology. We evaluated the cost-effective technique of thoracoscopic endoloop ligation of bullae in patients with bullous emphysema.

PATIENTS

From March 1992 through January 1996, 79 advanced age (mean age, 64 years) and oxygen dependency patients underwent thoracoscopic procedure using endoloop ligation for treatment of bullous emphysema. Clinical data were collected from chart review. Only patients with radiographically confirmed diagnosis of bullous emphysema were included in this evaluation. Thoracoscopic endoloop ligation of bulla was carried out under general anesthesia with double-lumen endotracheal tube and single-lung ventilation.

RESULTS

Sixty-five patients (82%) exhibited subjective improvement in their symptom status at 3-month follow-up (from grade 2 or 3 to grade 1 or 2) according to the Modified Medical Research Council dyspnea scale. The mean duration of chest drainage was 6 days (range, 4 to 16 days). Average hospital stay was 9.5 days (range, 5 to 26 days). There was no postoperative death. A comparison of preoperative and postoperative functional evaluation was available in only 16 patients who showed an increase in FEV1 (from 0.85 to 1.02 L) and a decline in residual volume after operation. Complications include persistent airleak over 10 days in seven patients (8.9%), wound infection in three patients, and localized empyema in two patients. There was no recurrence after a mean follow-up of 21 months.

CONCLUSION

These encouraging results have shown that thoracoscopic endoloop ligation of bulla has proved to be a safe, reliable, and cost-effective technique for bullous emphysema. With careful preoperative evaluation and meticulous postoperative care, many patients could be rehabilitated by endoloop litigation of the bullae.

摘要

研究目的

随着电视辅助胸腔镜手术的改进,越来越多的老年患者和呼吸功能受损的患者正在使用新的昂贵技术进行肺大疱消融术。我们评估了胸腔镜下用Endoloop结扎法治疗大疱性肺气肿患者的成本效益技术。

患者

从1992年3月至1996年1月,79例高龄(平均年龄64岁)且依赖氧气的患者接受了胸腔镜下使用Endoloop结扎法治疗大疱性肺气肿的手术。通过查阅病历收集临床数据。本评估仅纳入经影像学确诊为大疱性肺气肿的患者。胸腔镜下肺大疱Endoloop结扎术在全身麻醉下使用双腔气管插管和单肺通气进行。

结果

根据改良医学研究委员会呼吸困难量表,65例患者(82%)在3个月随访时症状状态有主观改善(从2级或3级改善至1级或2级)。胸腔引流的平均持续时间为6天(范围4至16天)。平均住院时间为9.5天(范围5至26天)。无术后死亡病例。仅16例患者可进行术前和术后功能评估比较,这些患者术后第一秒用力呼气容积增加(从0.85升至1.02升),残气量下降。并发症包括7例患者(8.9%)持续漏气超过10天、3例患者伤口感染和2例患者局限性脓胸。平均随访21个月后无复发。

结论

这些令人鼓舞的结果表明,胸腔镜下肺大疱Endoloop结扎术已被证明是一种治疗大疱性肺气肿安全、可靠且具有成本效益的技术。通过仔细的术前评估和精心的术后护理,许多患者可通过肺大疱Endoloop结扎术康复。

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