An investigation of polymorphism in the interleukin-10 gene promoter.
作者信息
Turner D M, Williams D M, Sankaran D, Lazarus M, Sinnott P J, Hutchinson I V
机构信息
Tissue Typing Laboratory, St Mary's Hospital, Manchester, UK.
出版信息
Eur J Immunogenet. 1997 Feb;24(1):1-8. doi: 10.1111/j.1365-2370.1997.tb00001.x.
Abstract
Interleukin-10 (IL-10) has been described as an anti-inflammatory cytokine and B-cell proliferation factor and has been implicated in autoimmunity, tumorigenesis and transplantation tolerance. We have identified three single base pair substitutions in the IL-10 gene promoter and have investigated whether this polymorphism correlates with IL-10 protein production in vitro.
摘要
Zotero 插件