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[奥胡斯市立医院抗生素的使用情况。一项患病率研究]

[Utilization of antibiotics at the Arhus Municipal Hospital. A prevalence study].

作者信息

Tarp B D, Møller J K

机构信息

Arhus Universitetshospital, Arhus Kommunehospital, klinisk mikrobiologisk.

出版信息

Ugeskr Laeger. 1997 Feb 10;159(7):936-9.

PMID:9054084
Abstract

The hospital charts of 689 patients in Aarhus Municipal Hospital were surveyed on a single day in the autumn of 1994. Antibiotics were administered to 22% of the patients. In the intensive care unit, 69% of the patients received antibiotics, while 24% of the surgical patients and 17% of medical patients received antibiotics. Twenty-seven percent of 203 prescriptions were given as prophylaxis, mainly to surgical patients. Sixty-four percent were prescribed as monotherapy. Penicillins constituted 41% of the total usage of antibiotics. Antibiotics were administered orally in 55%, intravenously in 37%, topically in 5% and rectally in 3%. The prescription was noted in the medical chart for 96%, the indication in 74% and the planned duration of treatment in only 58% of the cases. Information concerning previous allergic reactions to penicillin was noted for 7% of the patients. It is concluded that the usage of antibiotics and the microbiological findings in the departments should be evaluated regularly, and the antibiotic regime and the practice of prescription adjusted accordingly.

摘要

1994年秋的某一天,对奥胡斯市立医院689名患者的病历进行了调查。22%的患者使用了抗生素。在重症监护病房,69%的患者使用了抗生素,而外科患者中有24%、内科患者中有17%使用了抗生素。203份处方中有27%用于预防,主要针对外科患者。64%的处方为单一疗法。青霉素占抗生素总使用量的41%。抗生素的给药方式为口服占55%,静脉注射占37%,局部用药占5%,直肠给药占3%。96%的病例在病历中有处方记录,74%有用药指征记录,而计划治疗疗程记录仅占58%。仅7%的患者记录了既往对青霉素过敏反应的信息。结论是,应定期评估各科室抗生素的使用情况和微生物学检查结果,并相应调整抗生素治疗方案和处方习惯。

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