Trombelli L, Scabbia A, Carotta V, Scapoli C, Calura G
Department of Periodontology, University of Ferrara, School of Dentistry, Italy.
Quintessence Int. 1996 Jan;27(1):19-25.
A controlled clinical trial was carried out to compare the clinical effect of combined antimicrobial-mechanical treatment modalities on moderate-to-deep periodontal pockets in patients with adult periodontitis. Twelve patients having at least three nonadjacent sites of periodontitis were included in the split-mouth study. Gingival Index, Plaque Record, bleeding on probing, probing depth, attachment level, and recession depth were recorded immediately before treatment. In the control site, supragingival and subgingival scaling was performed with an ultrasonic scaler. One experimental site received supplemental irrigation with 15 mL of a 100-mg/mL tetracycline solution, while the other received a tetracycline-loaded fiber after mechanical instrumentation. Fibers were left in place for 10 days. Reevaluation 30 and 60 days after treatment showed that all three treatment modalities were effective in improving clinical parameters. No adjunctive effect on the healing response was obtained by augmenting mechanical debridement with tetracycline.
进行了一项对照临床试验，以比较联合抗菌-机械治疗方式对成人牙周炎患者中至深牙周袋的临床效果。12名至少有三个不相邻牙周炎部位的患者被纳入了这项分口研究。在治疗前立即记录牙龈指数、菌斑记录、探诊出血、探诊深度、附着水平和退缩深度。在对照部位，用超声洁治器进行龈上和龈下刮治。一个试验部位接受15 mL 100 mg/mL四环素溶液的补充冲洗，而另一个试验部位在机械治疗后接受含四环素的纤维。纤维留置10天。治疗后30天和60天的重新评估表明，所有三种治疗方式在改善临床参数方面均有效。用四环素增强机械清创对愈合反应没有附加作用。
