Paracha P I, Hameed A, Simon J, Jamil A, Nawab G
Department of Human Nutrition, NWFP Agricultural University, Peshawar.
J Pak Med Assoc. 1997 Feb;47(2):49-53.
Iron deficiency anaemia is a serious problem among Pakistani children. Pre-intervention haematological status of children under two years was assessed as part of a double-blind, randomized controlled community-based study conducted in two semi-urban areas of Peshawar. The primary objective was to assess the impact of iron deficiency anaemia and iron intervention on growth and morbidity. Three hundred and twenty children who met the criteria of a "healthy child" were recruited for the study. Blood samples were drawn from 275 children for haemoglobin (Hb) and serum ferritin (SF) analyses. The children were classified as anaemic (Hb < 11 g/dl); iron deficient (SF < 12 ng/ml) and iron deficient anaemic (Hb < 11 g/dl and SF < 12 ng/ml). Ninety percent of the children were anaemic, 67% iron deficient and 63% iron deficient anaemic. Anaemia was more prevalent in boys who had significantly lower Hb and SF values than girls. The magnitude of anaemia in these children tended to increase with age. The study demonstrates that iron deficiency is the predominant cause of anaemia (69%) in children under two years. Minimization of iron deficiency anaemia should be a public health priority in order to prevent suffering of children and avert the associated cognitive and physical deficits in child development.
缺铁性贫血是巴基斯坦儿童中的一个严重问题。作为在白沙瓦两个半城市地区开展的一项双盲、随机对照社区研究的一部分,对两岁以下儿童干预前的血液学状况进行了评估。主要目的是评估缺铁性贫血和铁干预对生长及发病率的影响。符合“健康儿童”标准的320名儿童被纳入该研究。采集了275名儿童的血样进行血红蛋白(Hb)和血清铁蛋白(SF)分析。这些儿童被分类为贫血(Hb < 11 g/dl);缺铁(SF < 12 ng/ml)和缺铁性贫血(Hb < 11 g/dl且SF < 12 ng/ml)。90%的儿童贫血,67%缺铁,63%缺铁性贫血。贫血在男孩中更为普遍,他们的Hb和SF值显著低于女孩。这些儿童的贫血程度往往随年龄增长而增加。该研究表明,缺铁是两岁以下儿童贫血的主要原因(69%)。为防止儿童受苦并避免儿童发育中相关的认知和身体缺陷,将缺铁性贫血降至最低应成为公共卫生的优先事项。