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异戊巴比妥钠记忆测试:它们能预测什么?

Sodium amobarbital memory tests: what do they predict?

作者信息

Dade L A, Jones-Gotman M

机构信息

Montreal Neurological Institute and Hospital, McGill University, Canada.

出版信息

Brain Cogn. 1997 Mar;33(2):189-209. doi: 10.1006/brcg.1997.0892.

DOI:10.1006/brcg.1997.0892
PMID:9073373
Abstract

Severe transient postoperative memory deficits among epilepsy patients with resection from one temporal lobe may be indicative of increased risk for amnesia had more extensive removal of mesial structures occurred. Immediate postoperative testing may provide some validation for risk of amnesia as predicted by the intracarotid sodium amobarbital memory test (IAP-M). Thirty patients (24 not considered at risk for amnesia and 5 who failed the IAP-M) were tested on the first, second, and third days following resection from the right or left temporal lobe. Results suggest that the IAP-M paradigm used does not necessarily predict postoperative memory performance.

摘要

对于接受一侧颞叶切除术的癫痫患者,严重的术后短暂记忆缺陷可能表明,如果内侧结构切除范围更广,发生失忆的风险会增加。术后立即进行测试可能会为通过颈动脉注射戊巴比妥钠记忆测试(IAP-M)预测的失忆风险提供一些验证。对30例患者(24例不被认为有失忆风险,5例IAP-M测试未通过)在右侧或左侧颞叶切除术后的第一天、第二天和第三天进行了测试。结果表明,所使用的IAP-M模式不一定能预测术后记忆表现。

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