避免氟喹诺酮耐药性。基层医疗实践策略。

Avoiding fluoroquinolone resistance. Strategies for primary care practice.

作者信息

Stratton C W

机构信息

Vanderbilt University School of Medicine, Nashville, Department of Pathology, Vanderbilt University School of Medicine, TN 37232-2561, USA.

出版信息

Postgrad Med. 1997 Mar;101(3):247-50, 255. doi: 10.3810/pgm.1997.03.186.

DOI:10.3810/pgm.1997.03.186

PMID:9074562

Abstract

The therapeutic usefulness of fluroquinolones for serious and difficult-to-treat infections is well documented. However, with increasing reports of organisms becoming resistant to the agents (most often the pseudomonads, staphylococci, and streptococci), the usefulness of this class of antibiotics is being threatened. Appropriate and judicious prescribing of this class of antimicrobials can greatly aid in preserving the therapeutic value of fluoroquinolones for the treatment of infections in the future.

摘要

氟喹诺酮类药物在治疗严重及难治性感染方面的疗效已有充分记录。然而，随着越来越多关于微生物对这类药物产生耐药性（最常见的是假单胞菌属、葡萄球菌属和链球菌属）的报道，这类抗生素的有效性正受到威胁。合理且明智地使用这类抗菌药物，对于在未来保持氟喹诺酮类药物治疗感染的疗效有极大帮助。