Adachi Y, Oshiro T, Mori M, Maehara Y, Sugimachi K
Second Department of Surgery, Faculty of Medicine, Kyushu University, Fukuoka, Japan.
Ann Surg Oncol. 1997 Mar;4(2):137-40. doi: 10.1007/BF02303796.
Tumor size can be measured easily before or during operation with no special tools, but its prognostic use in patients with gastric carcinoma is still unclear.
Clinicopathologic data of 479 patients who underwent curative operation for gastric carcinoma were studies. The relationship between tumor size and survival of patients was investigated.
The patients were divided into three groups: 182 with tumors measuring < 4 cm (group I), 252 with tumors of 4-10 cm (group II), and 45 with tumors of > or = 10 cm (group III). The 10-year survival rates for group I, II, and III patients were 92%, 66% and 33%, respectively (p < 0.01), and the three groups were significantly different with regard to depth of invasion (p < 0.01), number and level of lymph node metastasis (p < 0.01), and stage of disease (p < 0.01). Multivariate analysis indicated that tumor size independently influenced the survival of patients.
Tumor size clinically serves as a simple predictor of tumor progression and survival of patients in gastric carcinoma.
肿瘤大小在手术前或手术期间无需特殊工具即可轻松测量，但其在胃癌患者中的预后价值仍不明确。
对479例行胃癌根治性手术患者的临床病理资料进行研究。调查肿瘤大小与患者生存之间的关系。
患者分为三组：182例肿瘤直径<4 cm（I组），252例肿瘤直径为4 - 10 cm（II组），45例肿瘤直径≥10 cm（III组）。I组、II组和III组患者的10年生存率分别为92%、66%和33%（p<0.01），三组在浸润深度（p<0.01）、淋巴结转移数量和水平（p<0.01）以及疾病分期（p<0.01）方面存在显著差异。多因素分析表明肿瘤大小独立影响患者生存。
肿瘤大小在临床上可作为胃癌患者肿瘤进展和生存的简单预测指标。
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