Goss L R, Walter J H
Graduate Health System, Parkview Hospital, Philadelphia, PA, USA.
J Am Podiatr Med Assoc. 1997 Mar;87(3):136-40. doi: 10.7547/87507315-87-3-136.
A rare, large pediatric aneurysmal bone cyst with pathologic fracture of the distal tibia of a 4-year-old female was presented. Classic radiographic and magnetic resonance imaging findings have been discussed. In a comprehensive review of the literature, aneurysmal bone cysts are an infrequently reported neoplasm of the foot and ankle bones. Lesions are characteristically seen in patients younger than 20 years of age, but rarely younger than 5 years. The benign cyst has a 2:1 female-to male predilection. In long bones, the lesion is typically metaphyseal in nature. Although the pathogenesis is still unknown, there exists the possibility of two types of aneurysmal bone cysts: a primary type without preexisting lesion and a secondary form associated with some other lesion. The diagnosis of aneurysmal bone cyst can be strongly suspected by correlating the radiographic and magnetic resonance imaging findings. For definitive diagnosis, accurate histologic evaluation is imperative to rule out any confusion or possibility with a malignant tumor.
本文报告了一例罕见的大型儿童动脉瘤样骨囊肿,该囊肿发生于一名4岁女性患儿的胫骨远端,并伴有病理性骨折。文中讨论了其典型的X线和磁共振成像表现。在对文献的全面回顾中发现,动脉瘤样骨囊肿是一种在足踝部骨骼中报道较少的肿瘤。病变特征性地见于20岁以下的患者,但很少见于5岁以下的儿童。这种良性囊肿女性与男性的发病比例为2:1。在长骨中,病变通常位于干骺端。尽管其发病机制尚不清楚,但动脉瘤样骨囊肿可能存在两种类型:一种是无先前病变的原发性类型,另一种是与其他一些病变相关的继发性类型。通过结合X线和磁共振成像表现,可强烈怀疑动脉瘤样骨囊肿的诊断。为明确诊断,必须进行准确的组织学评估,以排除与恶性肿瘤的任何混淆或可能性。