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副泪腺的表面上的嗜酸细胞瘤

Ostensible oncocytoma of accessory lacrimal glands.

作者信息

Pecorella I, Garner A

机构信息

Dipartimento di Medicina Sperimentale e Patologia, Università La Sapienza, Rome, Italy.

出版信息

Histopathology. 1997 Mar;30(3):264-70. doi: 10.1046/j.1365-2559.1997.d01-601.x.

Abstract

Benign oncocytomas of the accessory lacrimal glands can be found in the lacrimal caruncle, plica semilunaris or conjunctival fornices, but are extremely rare. A series of 15 supposed oncocytomas of the ocular adnexa was reviewed retrospectively, and histological differences were noted with respect to the parotid gland counterpart. Lesions could be divided into three histological groups: (1) tumours composed of tubules lined by tall columnar epithelium with finely granular cytoplasm; the tubules often had dilated lumens containing mucinous secretion; (2) cystic tumours with prominent epithelial tufts projecting from much of the cyst wall; (3) tumours with solid areas composed of variably cuboidal or polygonal cells, largely in trabecular arrangement, and co-existing with the previously described tubular and cystic elements. A striking resemblance to Warthin's tumour without a lymphocytic component, such as may affect the parotid salivary gland, was noted in several tumours.

摘要

副泪腺的良性嗜酸细胞瘤可发生于泪阜、半月襞或结膜穹窿,但极为罕见。回顾性分析了一系列15例疑似眼附属器嗜酸细胞瘤,观察到其与腮腺同类肿瘤在组织学上的差异。病变可分为三个组织学组:(1)由高柱状上皮衬里的小管组成的肿瘤,细胞质呈细颗粒状;小管的管腔常扩张,内含黏液性分泌物;(2)囊性肿瘤,囊壁大部分有突出的上皮性绒毛;(3)实性区域由大小不一的立方形或多边形细胞组成的肿瘤,主要呈小梁状排列,并与上述管状和囊性成分共存。在一些肿瘤中,观察到与沃辛瘤(Warthin's tumour)极为相似,但无淋巴细胞成分,后者可累及腮腺。

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