Saijo M, Fujita K
Department of Pediatrics, Asahikawa Medical College.
Nihon Rinsho. 1997 Apr;55(4):870-5.
Central nervous system infection caused by mumps virus is reviewed. Aseptic meningitis, acute encephalitis, chronic encephalitis, hydrocephalus, ataxia, transverse myelitis, Guillain-Barré syndrome and deafness are noted as central nervous system complications of mumps. Among these complications, acute and chronic encephalitis, hydrocephalus, transverse myelitis and deafness occasionally result in severe sequelae. Aseptic meningitis due to mumps vaccine strain increased significantly after the introduction of trivalent measles, mumps and rubella vaccination in Japan. Recently, a differentiation method of mumps vaccine strain from wild viruses has been established using molecular analysis. Mumps virus infection is still one of the most common communicable viral infections, although it is preventable by vaccination. We emphasize the importance of mumps vaccination to prevent such severe complications as encephalitis and deafness.
本文综述了由腮腺炎病毒引起的中枢神经系统感染。无菌性脑膜炎、急性脑炎、慢性脑炎、脑积水、共济失调、横贯性脊髓炎、吉兰-巴雷综合征和耳聋被认为是腮腺炎的中枢神经系统并发症。在这些并发症中，急性和慢性脑炎、脑积水、横贯性脊髓炎和耳聋偶尔会导致严重的后遗症。在日本引入三价麻疹、腮腺炎和风疹疫苗接种后，由腮腺炎疫苗株引起的无菌性脑膜炎显著增加。最近，利用分子分析建立了一种从野生病毒中区分腮腺炎疫苗株的方法。尽管腮腺炎病毒感染可通过接种疫苗预防，但它仍然是最常见的传染性病毒感染之一。我们强调接种腮腺炎疫苗对于预防脑炎和耳聋等严重并发症的重要性。
