Domanski J J, Nelson L A, Guthrie F E, Domanski R E, Mark R, Postlethwait R W
Arch Environ Health. 1977 Sep-Oct;32(5):196-9. doi: 10.1080/00039896.1977.10667280.
The adipose tissue of humans with known patterns of cigarette smoking was collected during 1973-74 and analyzed for DDT components and dieldrin. Although smokers are exposed to high levels of insecticides from smoke of cigarettes and some of these compounds can be stored in adipose tissue, it could not be demonstrated that a relationship exists between smoking habit and residual levels of DDT found in fat. Smokers seem able, through induction of enzymes by substances in tobacco smoke, to metabolize these insecticides at a rate approximately equal to the rate of their intake in the smoke. Dieldrin residues in black male subjects were found to be linearly related to the number of cigarettes smoked, but the factors governing this relationship were not obvious.
1973年至1974年间收集了已知吸烟模式的人类脂肪组织，并对其中的滴滴涕成分和狄氏剂进行了分析。尽管吸烟者会从香烟烟雾中接触到高浓度的杀虫剂，且其中一些化合物可储存在脂肪组织中，但无法证明吸烟习惯与脂肪中发现的滴滴涕残留水平之间存在关联。吸烟者似乎能够通过烟草烟雾中的物质诱导酶的产生，以大约等同于其从烟雾中摄入杀虫剂的速率来代谢这些杀虫剂。发现黑人男性受试者体内的狄氏剂残留量与吸烟数量呈线性相关，但控制这种关系的因素并不明确。
