Coexistence of a graft with the preserved native liver in auxiliary partial orthotopic liver transplantation from a living donor for ornithine transcarbamylase deficiency.
作者信息
Uemoto S, Yabe S, Inomata Y, Nishizawa H, Asonuma K, Egawa H, Kiuchi T, Okajima H, Yamaoka Y, Yamabe H, Inui A, Fujisawa T, Tanaka K
机构信息
Department of Transplantation and Immunology, Kyoto University Graduate School of Medicine, Kyoto University Hospital, Shogoin, Sakyo-ku, Japan.
出版信息
Transplantation. 1997 Apr 15;63(7):1026-8. doi: 10.1097/00007890-199704150-00021.
BACKGROUND
Auxiliary partial orthotopic liver transplantation (APOLT) has recently been performed in patients with noncirrhotic metabolic liver diseases. However, long-term outcomes for the preserved native liver and the transplanted liver graft have not been clearly established yet.
METHODS
The recipient was a 36-month-old girl with ornithine transcarbamylase deficiency. She underwent APOLT, using her father's left lateral segment.
RESULTS
Liver function was normalized soon after APOLT and the patient was able to ingest a normal diet without medication. Coexistence of the well-functioning native liver and graft was demonstrated in a computed tomography scan, Doppler ultrasonography, scintigraphy, and histological examination, during a relatively long-term follow-up period.
CONCLUSIONS
APOLT seems to be most useful for the treatment of noncirrhotic metabolic liver diseases.
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