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普通肠线、皮肤胶带和聚乙醇酸缝线用于皮肤缝合的比较:一项前瞻性临床试验。

A comparison of the use of plain catgut, skin tapes and polyglactin sutures for skin closure: a prospective clinical trial.

作者信息

Anatol T I, Roopchand R, Holder Y, Shing-Hon G

机构信息

Department of Surgery, Faculty of Medical Sciences, University of the West Indies, St. Augustine, Trinidad.

出版信息

J R Coll Surg Edinb. 1997 Apr;42(2):124-7.

PMID:9114686
Abstract

A prospective clinical trial was carried out to compare the effect, on wound healing, of the use of polyglactin, plain catgut sutures, or skin tapes, in the closure of 190 groin crease incisions in children. The final outcome variable analysed was uneventful healing, defined as the absence of wound erythema, induration, discharge, raw areas, stitch sinuses or extrusions, or spreading or thickening of the scar, at four successive observation periods, up to 11 months post-operatively. Wounds closed with polyglactin exhibited a significant advantage over either of the two other methods in the early postoperative period (P = < 0.5). This association diminished over subsequent observation periods. Skin tapes were cheapest and quickest to use, but gave rise to a high incidence of wound problems, particularly early separation of the skin edges. Patient age (P = < 0.01 to < 0.05) and sex (P < 0.01) also exercised an effect on wound outcome, particularly at the final observation point. The reason for this was not determined. The results of this trial favour the use of polyglactin sutures over plain catgut and skin tapes in the closure of groin crease incisions in the population studied.

摘要

开展了一项前瞻性临床试验,比较聚乙醇酸缝线、普通肠线或皮肤胶带在闭合190例儿童腹股沟皱襞切口时对伤口愈合的影响。分析的最终结局变量为顺利愈合,定义为术后长达11个月的四个连续观察期内无伤口红斑、硬结、渗液、创面、缝线窦道或缝线外露,或瘢痕无扩展或增厚。在术后早期,使用聚乙醇酸缝线闭合的伤口比其他两种方法中的任何一种都具有显著优势(P = < 0.5)。在随后的观察期内,这种关联减弱。皮肤胶带最便宜且使用最快,但会导致伤口问题发生率较高,尤其是皮肤边缘早期分离。患者年龄(P = < 0.01至< 0.05)和性别(P < 0.01)也对伤口结局有影响,尤其是在最后观察点。其原因未确定。该试验结果表明,在所研究人群中,闭合腹股沟皱襞切口时,使用聚乙醇酸缝线优于普通肠线和皮肤胶带。

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