Shashkin P N, Jiao Y, Westerblad H, Katz A
Division of Clinical Physiology, Department of Surgical Sciences, Karolinska Institute, Karolinska Hospital, Stockholm, Sweden.
Am J Physiol. 1997 Feb;272(2 Pt 1):E245-7. doi: 10.1152/ajpendo.1997.272.2.E245.
The effects of C-peptide on carbohydrate metabolism in isolated mouse soleus muscle were studied. C-peptide, at concentrations up to 1,000 nM, had no effect on [14C]glucose incorporation into glycogen, glycogen synthase activity, or 2-deoxyglucose uptake. These data demonstrate that C-peptide has no direct effect on the measured parameters of carbohydrate metabolism in isolated mouse muscle.