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双胞胎与早产

Twins and preterm labor.

作者信息

Rust O A, Perry K G, Andrew M E, Roberts W E, Martin R W, Morrison J C

机构信息

Department of Obstetrics and Gynecology, University of Mississippi Medical Center, Jackson 39216-4505, USA.

出版信息

J Reprod Med. 1997 Apr;42(4):229-34.

PMID:9131496
Abstract

OBJECTIVE

To assess the effect of home uterine contraction assessment (HUCA) in twin pregnancies with preterm labor (PTL) at < 24 weeks' gestation.

STUDY DESIGN

In this retrospective, analytic study, patients were stratified by whether HUCA had been prescribed before or after diagnosis of PTL. The main outcomes studied were time of PTL diagnosis and delivery as well as birth weight and need for neonatal intensive care unit (NICU) admission. In 63 patients, 32 were prescribed HUCA after PTL had been arrested at < 24 weeks (group I). Thirty-one women had HUCA prescribed at 20 weeks' gestational age and then developed PTL at < 24 weeks (group II).

RESULTS

Labor was diagnosed at similar times in both groups (22.8 vs 23.4 weeks), but delivery was earlier in group I (27.6 weeks vs. 34.7 weeks) than in group II. The birth weight in group I was less (918 +/- 255 g), and of the 64 infants, 55 required NICU admission as compared to 2,340 +/- 525 g and 11 of 62 infants (P < .0001, .0001) in group II, respectively.

CONCLUSION

Women with twin gestations and the diagnosis of PTL prior to 24 weeks deliver later in gestation, and their infants weigh more and have fewer NICU admissions if intensive prenatal surveillance is prescribed prior to the onset of labor.

摘要

目的

评估家庭子宫收缩评估(HUCA)对妊娠<24周的双胎早产(PTL)的影响。

研究设计

在这项回顾性分析研究中,根据PTL诊断前后是否开具HUCA对患者进行分层。研究的主要结局是PTL诊断和分娩时间以及出生体重和新生儿重症监护病房(NICU)收治需求。63例患者中,32例在PTL于<24周时得到控制后开具HUCA(I组)。31例女性在孕20周时开具HUCA,随后在<24周时发生PTL(II组)。

结果

两组PTL诊断时间相近(22.8周对23.4周),但I组分娩时间早于II组(27.6周对34.7周)。I组出生体重更低(918±255 g),64例婴儿中有55例需要入住NICU,而II组62例婴儿中分别为2340±525 g和11例(P<0.0001,0.0001)。

结论

妊娠<24周诊断为PTL的双胎妊娠女性,如果在分娩开始前进行强化产前监测,其妊娠晚期分娩时间更晚,婴儿体重更重,入住NICU的人数更少。

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