Blomgren L G
Department of Surgery, St. Göran Hospital, Stockholm, Sweden.
World J Surg. 1997 May;21(4):412-4; discussion 414-5. doi: 10.1007/pl00012263.
The relative incidence of peptic ulcer perforation in the elderly is rising, and the optimal surgical treatment has yet to be defined. To evaluate the long-term result after simple closure a follow-up study was initiated at a Swedish community hospital. During 1983-1992 a total of 151 patients were admitted with perforated peptic ulcer; 92 were elderly (i.e., 70 years or older), 63 of whom were operated with simple closure. Mortality at 30 days was 27% (17/63) and the total in-hospital mortality 30% (19/63). After a mean follow-up of 79 months, 14 of the 44 survivors are still alive. So far only three of the survivors have required additional hospitalization for complications of peptic ulcer disease. Because the rate of serious recurrences is low (14%, 6/44), it is concluded that simple closure is an adequate surgical treatment for peptic ulcer perforation in the elderly.
老年人消化性溃疡穿孔的相对发病率正在上升,而最佳手术治疗方法尚未确定。为了评估单纯缝合术后的长期效果,瑞典一家社区医院开展了一项随访研究。1983年至1992年期间,共有151例患者因消化性溃疡穿孔入院;92例为老年人(即70岁及以上),其中63例行单纯缝合手术。30天死亡率为27%(17/63),住院总死亡率为30%(19/63)。平均随访79个月后,44名幸存者中有14人仍在世。到目前为止,只有3名幸存者因消化性溃疡疾病并发症需要再次住院治疗。由于严重复发率较低(14%,6/44),得出结论:单纯缝合是老年人消化性溃疡穿孔的一种充分的手术治疗方法。