Wróbel M, Ubuka T, Yao W B, Abe T
Department of Biochemistry, Okayama University Medical School, Japan.
Comp Biochem Physiol B Biochem Mol Biol. 1997 Feb;116(2):223-6. doi: 10.1016/s0305-0491(96)00216-7.
Rhodanese, gamma-cystathionase and 3-mercaptopyruvate sulfurtransferase activities were examined in guinea pig and rat liver, kidney and brain. In the liver of both species rhodanese showed the same high range of activity but in guinea pig kidney and brain a slightly lower level was determined than that in corresponding rat tissues. The 3-mercaptopyruvate sulfurtransferase and gamma-cystathionase activities in all the investigated tissues of guinea pig were significantly lower than those in rat. The sulfane sulfur pool, a source of sulfur transferred by rhodanese, can be augmented in vitro in guinea pig liver, but not in rat liver when 3-mercaptolactate-cysteine disulfide is used as a substrate of gamma-cystathionase.
对豚鼠和大鼠的肝脏、肾脏及大脑中的硫氰酸酶、γ-胱硫醚酶和3-巯基丙酮酸硫转移酶活性进行了检测。在这两个物种的肝脏中，硫氰酸酶显示出相同的高活性范围，但在豚鼠的肾脏和大脑中，所测定的活性水平略低于相应大鼠组织中的水平。豚鼠所有被研究组织中的3-巯基丙酮酸硫转移酶和γ-胱硫醚酶活性均显著低于大鼠。当以3-巯基乳酸-半胱氨酸二硫化物作为γ-胱硫醚酶的底物时，作为硫氰酸酶转移硫来源的硫烷硫池在豚鼠肝脏中可在体外增加，但在大鼠肝脏中则不然。
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